N-Deacetylthiocolchicine

Base Information Edit

Chemical Name:N-Deacetylthiocolchicine
CAS No.:2731-16-0
Molecular Formula:C20H23 N O4 S
Molecular Weight:373.473
Hs Code.:2930909090
European Community (EC) Number:630-576-4
NSC Number:9170
DSSTox Substance ID:DTXSID90181756
Nikkaji Number:J21.179F
ChEMBL ID:CHEMBL298240
Mol file:2731-16-0.mol

Synonyms:N-Deacetylthiocolchicine;Thio-colciran;2731-16-0;Thiolcolciran;COLCHICINE, N-DEACETYL-10-THIO-;N-Desacetylthiocolchicine;Corps R. 261;N-Deacetylmethylthiocolchicine;Deacetylthiocolchicine;Colchicine, N-deacetyl-thio-;Desacetyl thiocolchicine;N-Desacetyl thiocolchicine;NSC9170;NSC 9170;BRN 2822164;Benzo(a)heptalen-9(5H)-one, 7-amino-6,7-dihydro-1,2,3-trimethoxy-10-(methylthio)-, (S)-;CHEMBL298240;R 261;N-Deacetyl-10-demethoxy-10-methylthiocolchicine;Colchicine, N-deacetyl-10-demethoxy-10-methylthio-;(7S)-7-amino-1,2,3-trimethoxy-10-methylsulfanyl-6,7-dihydro-5H-benzo[a]heptalen-9-one;(S)-7-Amino-1,2,3-trimethoxy-10-(methylthio)-6,7-dihydrobenzo[a]heptalen-9(5H)-one;MLS002702975;Benzo[a]heptalen-9(5H)-one, 7-amino-6,7-dihydro-1,2,3-trimethoxy-10-(methylthio)-, (S)-;N-desacetyl-thiocolchicine;N-Deacetyl-10-thiocolchicine;cid_426728;SCHEMBL5434553;DTXSID90181756;PKH 147;NSC-9170;BDBM50014875;AKOS040751238;LS-54680;NCI60_042026;CS-0104812;R-261;D76467;WLN: L B677 MV&T&J CO1 DO1 EO1 JZ NS1;(S)-7-Amino-1,2,3-trimethoxy-10-methylsulfanyl-6,7-dihydro-5H-benzo[a]heptalen-9-one;7-Amino-1,2,3-trimethoxy-10-methylsulfanyl-6,7-dihydro-5H-benzo[a]heptalen-9-one;Benzo[a]heptalen-9(5H)-one, 7-amino-6,7-dihydro-1,2,3-trimethoxy-10-(methylthio)-, (7S)-

Suppliers and Price of N-Deacetylthiocolchicine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
THIOCOLCIRAN 95.00%
5MG
$ 505.40

Total 8 raw suppliers

Chemical Property of N-Deacetylthiocolchicine Edit

Chemical Property:

Vapor Pressure:7.33E-16mmHg at 25°C
Melting Point:198 °C
Refractive Index:1.5800 (estimate)
Boiling Point:631.6°Cat760mmHg
PKA:8.62±0.40(Predicted)
Flash Point:335.8°C
PSA：96.08000
Density:1.27g/cm³
LogP:4.10780
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:373.13477939
Heavy Atom Count:26
Complexity:642

Purity/Quality:

99% ^*data from raw suppliers

THIOCOLCIRAN 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C(=C2C(=C1)CCC(C3=CC(=O)C(=CC=C32)SC)N)OC)OC
Isomeric SMILES:COC1=C(C(=C2C(=C1)CC[C@@H](C3=CC(=O)C(=CC=C32)SC)N)OC)OC

Technology Process of N-Deacetylthiocolchicine

There total 13 articles about N-Deacetylthiocolchicine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%