Corynecin II

Base Information

Chemical Name:Corynecin II
CAS No.:35098-52-3
Molecular Formula:C12H16N2O5
Molecular Weight:268.2658
Hs Code.:
Mol file:35098-52-3.mol

Synonyms:CORYNECIN II;(1RS,2RS)-1-(4-Nitro-phenyl)-2-propionylamino-propan-1,3-diol;

Suppliers and Price of Corynecin II

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
CorynecinII
5mg
$ 105.00

Cayman Chemical
Corynecin II ≥99%
1mg
$ 99.00

Cayman Chemical
Corynecin II ≥99%
5mg
$ 297.00

AK Scientific
n-[(1r,2r)-1,3-Dihydroxy-1-(4-nitrophenyl)propan-2-yl]propanamide
1mg
$ 233.00

Total 6 raw suppliers

Chemical Property of Corynecin II

Chemical Property:

Vapor Pressure:6.68E-14mmHg at 25°C
Boiling Point:571.5°Cat760mmHg
Flash Point:299.4°C
PSA：115.38000
Density:1.326g/cm³
LogP:1.42940

Purity/Quality:

98%Min ^*data from raw suppliers

CorynecinII ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Description Corynecin II is a chloramphenicol-like antibiotic originally isolated from Corynebacterium. It inhibits the growth of Gram-positive and Gram-negative bacteria, including S. faecalis, S. aureus, B. subtilis, E. coli, P. aeruginosa, P. vulgaris, S. sonnei, S. typhosa, and K. pneumoniae (MICs = 5.2-83 μg/ml).
Uses Corynecin II is a member of a naturally-occurring complex of chloramphenicol-like acyl nitrophenylpropylamines isolated from Corynebacterium hydrocarboclastus in 1972. Corynecin II is active against Gram positive and Gram negative bacteria. Although less potent than chloramphenicol, corynecin II shows a similar species selectivity. Corynecin II is a chloramphenicol-like acyl nitrophenylpropylamine.

Technology Process of Corynecin II

There total 5 articles about Corynecin II which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 119-62-0,716-61-0,2792-51-0,2792-52-1,2964-48-9,3689-55-2,63526-31-8,71115-69-0,140694-64-0
(1R,2R)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol

: 123-62-6
propionic acid anhydride

: 35098-52-3
(1R,2R)-1-(4-nitro-phenyl)-2-propionylamino-propane-1,3-diol

Guidance literature:: beim Behandeln des Reaktionsprodukts mit NaOH in wss.Aceton;
DOI:10.1021/ja01166a129

Reference yield:

: 857346-77-1
N-(4-nitro-phenacyl)-propionamide

: 35098-52-3,104741-21-1
(1RS,2RS)-1-(4-nitro-phenyl)-2-propionylamino-propane-1,3-diol

Guidance literature:: Multi-step reaction with 2 steps

1: aq.-ethanolic NaHCO₃

2: isopropyl alcohol

With sodium hydrogencarbonate; isopropyl alcohol;

Reference yield:

: 4740-22-1
2-amino-1-(4-nitro-phenyl)-ethanone

: 35098-52-3,104741-21-1
(1RS,2RS)-1-(4-nitro-phenyl)-2-propionylamino-propane-1,3-diol

Guidance literature:: Multi-step reaction with 3 steps

2: aq.-ethanolic NaHCO₃

3: isopropyl alcohol

With sodium hydrogencarbonate; isopropyl alcohol;