N-((Z)-2,3-Didehydro-N-(N-formyl-L-methionyl)leucyl)-L-phenylalanine methyl ester

Base Information

Chemical Name:N-((Z)-2,3-Didehydro-N-(N-formyl-L-methionyl)leucyl)-L-phenylalanine methyl ester
CAS No.:137320-56-0
Molecular Formula:C₂₂H₃₁N₃O₅S
Molecular Weight:449.571
Hs Code.:
Nikkaji Number:J899.616D
Mol file:137320-56-0.mol

Synonyms:delta Z Leu(2)fMLP-OMe;formyl-methionyl-delta(Z)-dehydroleucyl-phenylalanine methyl ester;HCO-Met-delta(Z)-Leu-Phe-OMe

Suppliers and Price of N-((Z)-2,3-Didehydro-N-(N-formyl-L-methionyl)leucyl)-L-phenylalanine methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of N-((Z)-2,3-Didehydro-N-(N-formyl-L-methionyl)leucyl)-L-phenylalanine methyl ester

Chemical Property:

Vapor Pressure:1.55E-23mmHg at 25°C
Boiling Point:768.6°Cat760mmHg
Flash Point:418.6°C
PSA：149.37000
Density:1.172g/cm³
LogP:3.93160
XLogP3:2.8
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:13
Exact Mass:449.19844227
Heavy Atom Count:31
Complexity:633

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C=C(C(=O)NC(CC1=CC=CC=C1)C(=O)OC)NC(=O)C(CCSC)NC=O
Isomeric SMILES:CC(C)/C=C(\C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)OC)/NC(=O)[C@H](CCSC)NC=O

Technology Process of N-((Z)-2,3-Didehydro-N-(N-formyl-L-methionyl)leucyl)-L-phenylalanine methyl ester

There total 4 articles about N-((Z)-2,3-Didehydro-N-(N-formyl-L-methionyl)leucyl)-L-phenylalanine methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 80465-33-4
4-isobutylidene-oxazolidine-2,5-dione

: 137320-56-0
For-Met-Δ^ZLeu-Phe-OMe

Guidance literature:: Multi-step reaction with 3 steps

1: DCC, pyridine

2: N-methylmorpholine

3: N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ)

With 4-methyl-morpholine; pyridine; N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; dicyclohexyl-carbodiimide;
DOI:10.1016/S0040-4039(00)92174-9

Reference yield:

: 2488-15-5
N-tert-butoxycarbonyl-L-methionine

: 137320-56-0
For-Met-Δ^ZLeu-Phe-OMe

Guidance literature:: Multi-step reaction with 3 steps

1: DCC, pyridine

2: N-methylmorpholine

3: N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ)

With 4-methyl-morpholine; pyridine; N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; dicyclohexyl-carbodiimide;
DOI:10.1016/S0040-4039(00)92174-9

Reference yield:

: 137320-57-1
((S)-1-{4-[2-Methyl-prop-(Z)-ylidene]-2,5-dioxo-oxazolidine-3-carbonyl}-3-methylsulfanyl-propyl)-carbamic acid tert-butyl ester

: 137320-56-0
For-Met-Δ^ZLeu-Phe-OMe

Guidance literature:: Multi-step reaction with 2 steps

1: N-methylmorpholine

2: N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ)

With 4-methyl-morpholine; N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline;
DOI:10.1016/S0040-4039(00)92174-9