2,4-Dibromo-6-iodoaniline

Base Information

• Chemical Name: 2,4-Dibromo-6-iodoaniline
• CAS No.: 697-87-0
• Molecular Formula: C6H4Br2IN
• Molecular Weight: 376.817
• DSSTox Substance ID: DTXSID701307525
• Mol file: 697-87-0.mol

Synonyms:2,4-dibromo-6-iodoaniline;697-87-0;Benzenamine, 2,4-dibromo-6-iodo-;2,4-dibromo-6-iodobenzenamine;SCHEMBL19723645;DTXSID701307525

Chemical Property of 2,4-Dibromo-6-iodoaniline

Chemical Property:

• XLogP3: 3.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 376.77347
• Heavy Atom Count: 10
• Complexity: 122

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C(C=C(C(=C1Br)N)I)Br

Technology Process of 2,4-Dibromo-6-iodoaniline

There total 4 articles about 2,4-Dibromo-6-iodoaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

2,4-dibromo-aniline (615-57-6) → 2,4-dibromo-6-iodoaniline (697-87-0)

Guidance literature:

With iodine; silver sulfate; In ethanol; at 20 ℃; for 3h;

DOI:10.1016/S0040-4020(03)00073-5

Reference yield: 46.0%

2-iodophenylamine (615-43-0) → 4-bromo-2-iodoaniline (66416-72-6) + 2,4-dibromo-6-iodoaniline (697-87-0)

Guidance literature:

2-iodophenylamine; With n-butyllithium; In diethyl ether; hexane; at -78 ℃; for 1h;

With poly[4-(dibutyliodostannyl)butyl]styrene; In diethyl ether; hexane; at 20 ℃; for 18h;

With bromine; In diethyl ether; hexane; dichloromethane; at -78 - 20 ℃; for 2h;

DOI:10.1021/jo0480141

Reference yield:

2-amino-3,5-dibromo-benzenesulfonic acid → 2,4-dibromo-6-iodoaniline (697-87-0)

Guidance literature:

With Iodine monochloride; acetic acid;

upstream raw materials:

2,4-dibromo-aniline

2-iodophenylamine

2-amino-5-bromobenzenesulfonic acid

Downstream raw materials:

1,3-dibromo-5-iodobenzene

2,4-dibromo-6-[(trimethylsilyl)ethynyl]aniline

2,4-dibromo-6-iodonitrobenzene

2,4-dibromo-6-ethynylaniline