N,N'-dibenzylbutanediamide

Base Information

• Chemical Name: N,N'-dibenzylbutanediamide
• CAS No.: 71067-27-1
• Molecular Formula: C18H20N2O2
• Molecular Weight: 296.369
• DSSTox Substance ID: DTXSID70389617
• Nikkaji Number: J2.541.511F
• Wikidata: Q82185577
• ChEMBL ID: CHEMBL1714054
• Mol file: 71067-27-1.mol

Synonyms:N,N'-dibenzylbutanediamide;N,N'-Dibenzyl-succinamide;N,N'-Dibenzylsuccinamide;71067-27-1;MLS001203672;CHEMBL1714054;DTXSID70389617;HMS2820K04;N,N'-dibenzyl-butanedioic acid amide;AKOS000546839;SMR000516659;SR-01000313377;SR-01000313377-1

Chemical Property of N,N'-dibenzylbutanediamide

Chemical Property:

• XLogP3: 1.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 7
• Exact Mass: 296.152477885
• Heavy Atom Count: 22
• Complexity: 311

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)CNC(=O)CCC(=O)NCC2=CC=CC=C2

Technology Process of N,N'-dibenzylbutanediamide

There total 11 articles about N,N'-dibenzylbutanediamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

succinic acid (110-15-6) + benzylamine (100-46-9) → N1,N4-dibenzylsuccinamide (71067-27-1)

Guidance literature:

With 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride; In water; at 20 ℃; for 5h;

DOI:10.1016/S0040-4020(00)01137-6

Reference yield: 90.0%

Succinimide (123-56-8,89963-74-6) + benzylamine (100-46-9) → N1,N4-dibenzylsuccinamide (71067-27-1)

Guidance literature:

With 1,2,3-Benzotriazole; In neat (no solvent); at 130 ℃; for 24h; Inert atmosphere;

DOI:10.3987/COM-13-S(S)41

Reference yield: 86.0%

1-hydroxy-pyrrolidine-2,5-dione (6066-82-6) + benzylamine (100-46-9) → N1,N4-dibenzylsuccinamide (71067-27-1)

Guidance literature:

In methanol; for 0.75h; Ambient temperature;

upstream raw materials:

Succinimide

benzylamine

succinoyl dichloride

3-cyano-propionic acid methyl ester