2-Phenylpyrazolo[1,5-a]pyridine-3-carbaldehyde

Base Information

Chemical Name:2-Phenylpyrazolo[1,5-a]pyridine-3-carbaldehyde
CAS No.:71727-37-2
Molecular Formula:C14H10N2O
Molecular Weight:222.246
Hs Code.:
DSSTox Substance ID:DTXSID60569300
Wikidata:Q82456423

Synonyms:2-Phenylpyrazolo[1,5-a]pyridine-3-carbaldehyde;71727-37-2;SCHEMBL8811759;DTXSID60569300;GSGVFADOGIAWSM-UHFFFAOYSA-N;2-phenylpyrazolo[1,5-a]-pyridine-3-carbaldehyde;EN300-7425981;Z3846782236

Suppliers and Price of 2-Phenylpyrazolo[1,5-a]pyridine-3-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 2-Phenylpyrazolo[1,5-a]pyridine-3-carbaldehyde

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:222.079312947
Heavy Atom Count:17
Complexity:275

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=NN3C=CC=CC3=C2C=O

Technology Process of 2-Phenylpyrazolo[1,5-a]pyridine-3-carbaldehyde

There total 5 articles about 2-Phenylpyrazolo[1,5-a]pyridine-3-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 56983-95-0
2-phenylpyrazolo[1,5-a]pyridine

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 71727-37-2
2-phenyl-pyrazolo[1,5-a]pyridine-3-carbaldehyde

Guidance literature:: With trichlorophosphate;
DOI:10.1016/0960-894X(96)00368-X

Reference yield:

: 2216-94-6
phenylpropynoic acid ethyl ester

: 71727-37-2
2-phenyl-pyrazolo[1,5-a]pyridine-3-carbaldehyde

Guidance literature:: Multi-step reaction with 3 steps

1: potassium carbonate / N,N-dimethyl-formamide / 24 h / 20 °C

2: lithium aluminium tetrahydride / tetrahydrofuran / 20 °C / Cooling

3: manganese(IV) oxide / tetrahydrofuran / 1.5 h / Reflux

With manganese(IV) oxide; lithium aluminium tetrahydride; potassium carbonate; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1021/jm200388e

Reference yield:

: 51065-76-0
ethyl 2-phenylpyrazolo<1,5-a>pyridine-3-carboxylate

: 71727-37-2
2-phenyl-pyrazolo[1,5-a]pyridine-3-carbaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: lithium aluminium tetrahydride / tetrahydrofuran / 20 °C / Cooling

2: manganese(IV) oxide / tetrahydrofuran / 1.5 h / Reflux

With manganese(IV) oxide; lithium aluminium tetrahydride; In tetrahydrofuran;
DOI:10.1021/jm200388e