L-Leucyl-N-(4-nitrophenyl)glycinamide

Base Information

Chemical Name:L-Leucyl-N-(4-nitrophenyl)glycinamide
CAS No.:71732-39-3
Molecular Formula:C₁₄H₂₀N₄O₄
Molecular Weight:308.337
Hs Code.:
DSSTox Substance ID:DTXSID80557800
Wikidata:Q82439823

Synonyms:L-Leucyl-N-(4-nitrophenyl)glycinamide;71732-39-3;DTXSID80557800

Suppliers and Price of L-Leucyl-N-(4-nitrophenyl)glycinamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of L-Leucyl-N-(4-nitrophenyl)glycinamide

Chemical Property:

XLogP3:1.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:308.14845513
Heavy Atom Count:22
Complexity:400

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)CC(C(=O)NCC(=O)NC1=CC=C(C=C1)[N+](=O)[O-])N
Isomeric SMILES:CC(C)C[C@@H](C(=O)NCC(=O)NC1=CC=C(C=C1)[N+](=O)[O-])N

Technology Process of L-Leucyl-N-(4-nitrophenyl)glycinamide

There total 3 articles about L-Leucyl-N-(4-nitrophenyl)glycinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 123529-87-3
((S)-3-Methyl-1-{[(4-nitro-phenylcarbamoyl)-methyl]-carbamoyl}-butyl)-carbamic acid benzyl ester

: 71732-39-3
leucyl-glycine p-nitroanilide

Guidance literature:: With hydrogen bromide; In acetic acid; for 1.5h;

Reference yield:

: 2018-66-8
Z-Leu-OH

: 71732-39-3
leucyl-glycine p-nitroanilide

Guidance literature:: Multi-step reaction with 2 steps

1: 53 percent / DCC / CH₂Cl₂ / 12 h / 3 °C

2: 64 percent / HBr / acetic acid / 1.5 h

With hydrogen bromide; dicyclohexyl-carbodiimide; In dichloromethane; acetic acid;

Reference yield:

: 1205-88-5
glycine p-nitroanilide

: 71732-39-3
leucyl-glycine p-nitroanilide

Guidance literature:: Multi-step reaction with 2 steps

1: 53 percent / DCC / CH₂Cl₂ / 12 h / 3 °C

2: 64 percent / HBr / acetic acid / 1.5 h

With hydrogen bromide; dicyclohexyl-carbodiimide; In dichloromethane; acetic acid;