Butanedioic acid, chloro-, diethyl ester

Base Information

• Chemical Name: Butanedioic acid, chloro-, diethyl ester
• CAS No.: 7209-04-3
• Molecular Formula: C₈H₁₃ClO₄
• Molecular Weight: 208.642
• Mol file: 7209-04-3.mol

Synonyms:

Chemical Property of Butanedioic acid, chloro-, diethyl ester

Chemical Property:

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Butanedioic acid, chloro-, diethyl ester

There total 11 articles about Butanedioic acid, chloro-, diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

L(-)-diethyl malate (626-11-9,691-84-9,7554-12-3,7554-28-1) → D(+)-2-chlorosuccinate (7209-04-3,58175-67-0,116698-43-2,377751-51-4)

Guidance literature:

With diethyl(trichloromethyl)phosphine; triethylamine; In dichloromethane; for 12h; Ambient temperature;

Reference yield:

succinic acid diethyl ester (123-25-1) → diethyl chlorosuccinate (7209-04-3,116698-43-2,377751-51-4)

Guidance literature:

With tetrachloromethane; sulfuryl dichloride; dibenzoyl peroxide;

DOI:10.1021/ja01868a001

Reference yield:

diethylmalate (7554-12-3) → diethyl chlorosuccinate (7209-04-3,116698-43-2,377751-51-4)

Guidance literature:

With pyridine; thionyl chloride; d-chlorosuccinic acid diethyl ester;

upstream raw materials:

diazo-succinic acid diethyl ester

ethanol

chlorosuccinic acid

diethylmalate

Downstream raw materials:

4-oxo-4-phenyl-butane-1,2,3-tricarboxylic acid triethyl ester

propane-1,1,2,3-tetracarboxylic acid tetraethyl ester

diethyl 2-(benzylamino)succinate

Refernces

• 1、 Weisz, A.,Mandelbaum, A.,Blum, W.,Domon, B.,Muller, D,et. al.. "Application of Low Energy CID in the Determination of Structures of + Ions Obtained From Diethyl Halosuccinates Under Electron Impact". . p. 61 - 63. Retrieved 2007/10/02.