4-Methoxypyrimidine-5-carboxylic Acid

Base Information

Chemical Name:4-Methoxypyrimidine-5-carboxylic Acid
CAS No.:72411-89-3
Molecular Formula:C6H6N2O3
Molecular Weight:154.125
Hs Code.:2933599590
DSSTox Substance ID:DTXSID901287325
Mol file:72411-89-3.mol

Synonyms:4-Methoxypyrimidine-5-carboxylic Acid;72411-89-3;5-Pyrimidinecarboxylic acid, 4-methoxy-;4-Methoxy-5-pyrimidinecarboxylic acid;MFCD20644991;4-Methoxypyrimidine-5-carboxylicAcid;AMY159;SCHEMBL17157424;WMSJDLVVPJFZBF-UHFFFAOYSA-N;DTXSID901287325;XCA41189;AKOS022635081;5-Pyrimidinecarboxylic acid,4-methoxy-;DS-7582;SB57771;SY026698;CS-0043302;FT-0720792;F2147-8633

Suppliers and Price of 4-Methoxypyrimidine-5-carboxylic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Methoxy-5-pyrimidinecarboxylicAcid
250mg
$ 225.00

SynQuest Laboratories
4-Methoxypyrimidine-5-carboxylic acid
250 mg
$ 336.00

SynQuest Laboratories
4-Methoxypyrimidine-5-carboxylic acid
1 g
$ 784.00

Crysdot
4-Methoxypyrimidine-5-carboxylicacid 95+%
1g
$ 347.00

Crysdot
4-Methoxypyrimidine-5-carboxylicacid 95+%
5g
$ 891.00

Chemenu
4-methoxypyrimidine-5-carboxylicacid 95%
5g
$ 941.00

Chemenu
4-methoxypyrimidine-5-carboxylicacid 95%
10g
$ 1593.00

Chemenu
4-methoxypyrimidine-5-carboxylicacid 95%
1g
$ 370.00

Apolloscientific
4-Methoxypyrimidine-5-carboxylicacid
1g
$ 711.00

Apolloscientific
4-Methoxypyrimidine-5-carboxylicacid
250mg
$ 305.00

Total 11 raw suppliers

Chemical Property of 4-Methoxypyrimidine-5-carboxylic Acid

Chemical Property:

Melting Point:200 °C(Solv: N,N-dimethylformamide (68-12-2))
Boiling Point:334.7±22.0 °C(Predicted)
PKA:3.06±0.16(Predicted)
PSA：72.31000
Density:1.371±0.06 g/cm3(Predicted)
LogP:0.18340
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:0
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:154.03784206
Heavy Atom Count:11
Complexity:151

Purity/Quality:

97% ^*data from raw suppliers

4-Methoxy-5-pyrimidinecarboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=NC=NC=C1C(=O)O
Uses 4-Methoxy-5-pyrimidinecarboxylic Acid is used in the synthesis of 3-nortropane derivatives which possess anti-psychotic activity.

Technology Process of 4-Methoxypyrimidine-5-carboxylic Acid

There total 2 articles about 4-Methoxypyrimidine-5-carboxylic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 84332-00-3
methyl 4-methoxypyrimidine-5-carboxylate

: 72411-89-3
4-methoxy-5-pyrimidinyl carboxylic acid

Guidance literature:: With sodium hydroxide; In methanol; water; at 65 ℃; for 1h; Yield given;

Reference yield:

: 41103-17-7
ethyl 4-chloropyrimidine-5-carboxylate

: 72411-89-3
4-methoxy-5-pyrimidinyl carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 64 percent / sodium / Ambient temperature

2: NaOH / methanol; H₂O / 1 h / 65 °C

With sodium hydroxide; sodium; In methanol; water;

Reference yield: 57.0%

: 1356483-58-3
N¹‐cyclopropyl‐4,5‐difluorobenzene‐1,2‐diamine

: 72411-89-3
4-methoxy-5-pyrimidinyl carboxylic acid

: N-(2-(cyclopropylamino)-4,5-difluorophenyl)-4-methoxypyrimidine-5-carboxamide

Guidance literature:: With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In N,N-dimethyl-formamide; at 20 ℃; for 16h; Inert atmosphere;