4-Nitrophenyl beta-D-Fucopyranoside

Base Information

• Chemical Name: 4-Nitrophenyl beta-D-Fucopyranoside
• CAS No.: 1226-39-7
• Molecular Formula: C12H15 N O7
• Molecular Weight: 285.254
• Hs Code.: 2932999099
• DSSTox Substance ID: DTXSID90370002
• Nikkaji Number: J489.549E
• Wikidata: Q72495409
• Mol file: 1226-39-7.mol

Synonyms:1226-39-7;4-Nitrophenyl beta-D-Fucopyranoside;4-NITROPHENYL-BETA-D-FUCOPYRANOSIDE;4-Nitrophenyl b-D-fucopyranoside;(2R,3R,4S,5R,6S)-2-methyl-6-(4-nitrophenoxy)oxane-3,4,5-triol;b-D-Galactopyranoside,4-nitrophenyl 6-deoxy-;p-nitrophenyl beta-d-fucopyranoside;4-Nitrophenyl |A-D-fuco-pyran-oside;PNP-b-D-Fuc;4-Nitrophenyl 6-deoxy-beta-D-galactopyranoside;SCHEMBL150880;4-Nitrophenylb-D-fucopyranoside;DTXSID90370002;4-Nitrophenyl beta -D-fucopyranoside;MFCD00040651;2-Nitrophenyl I(2)-D-fucopyranoside;4-Nitrophenyl I(2)-D-fucopyranoside;AKOS015918201;4-Nitrophenyl Beta-D-fuco-pyran-oside;AM84358;AS-66583;HY-134455;CS-0142472;4-piperidinemethanol, 1-(4-pyridinylmethyl)-;D91773;beta-D-Galactopyranoside, 4-nitrophenyl 6-deoxy-;4-Nitrophenyl beta-D-fuco??pyran??oside, >=98% (TLC);(2R,3R,4S,5R,6S)-2-methyl-6-(4-nitrophenoxy)tetrahydro-2H-pyran-3,4,5-triol

Chemical Property of 4-Nitrophenyl beta-D-Fucopyranoside

Chemical Property:

• Vapor Pressure: 1.9E-11mmHg at 25°C
• Melting Point: 191-192oC
• Refractive Index: -75 ° (C=1, EtOH)
• Boiling Point: 515.4oC at 760 mmHg
• PKA: 12.68±0.70(Predicted)
• Flash Point: 265.5oC
• PSA: 124.97000
• Density: 1.503g/cm3
• LogP: 0.32430
• Storage Temp.: −20°C
• XLogP3: 0.1
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 2
• Exact Mass: 285.08485182
• Heavy Atom Count: 20
• Complexity: 339

Purity/Quality:

98%, ^*data from raw suppliers

4-Nitrophenyl b-D-fucopyranoside ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC1C(C(C(C(O1)OC2=CC=C(C=C2)[N+](=O)[O-])O)O)O
• Isomeric SMILES: C[C@@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)OC2=CC=C(C=C2)[N+](=O)[O-])O)O)O
• Uses: 4-Nitrophenyl beta-D-Fucopyranoside (cas# 1226-39-7) is a compound useful in organic synthesis.

Technology Process of 4-Nitrophenyl beta-D-Fucopyranoside

There total 9 articles about 4-Nitrophenyl beta-D-Fucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.5%

p-nitrophenyl 2,3,4-tri-O-acetyl-β-D-fucopyranoside (84729-97-5) → p-nitrophenyl-β-D-fucopyranoside (1226-39-7)

Guidance literature:

With sodium methylate; In methanol; at 4 ℃;

DOI:10.1016/0008-6215(83)88286-X

Reference yield: 63.6%

4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) + 2,3,4‐tri‐O‐acetyl-α-L‐rhamnopyranosyl chloride (5160-09-8) → p-nitrophenyl α-L-rhamnopyranoside (1226-39-7,10231-84-2,18918-31-5,22153-71-5,33095-26-0,73351-15-2,74032-91-0,140387-70-8)

Guidance literature:

With tetrabutylammomium bromide; sodium hydroxide; In dichloromethane; at 30 ℃; for 4.5h; Reagent/catalyst;

DOI:10.1080/07328303.2017.1390578

Reference yield:

4-nitrophenyl-2,3,4,6-tetra-O-acetyl-α-L-rhamnopyranoside (18992-37-5) → p-nitrophenyl α-L-rhamnopyranoside (1226-39-7,10231-84-2,18918-31-5,22153-71-5,33095-26-0,73351-15-2,74032-91-0,140387-70-8)

Guidance literature:

With methanol; sodium methylate;

upstream raw materials:

4-nitrophenyl-2,3,4,6-tetra-O-acetyl-α-L-rhamnopyranoside

4-nitro-phenol

2,3,4‐tri‐O‐acetyl-α-L‐rhamnopyranosyl chloride

p-nitrophenyl 2,3,4-tri-O-acetyl-β-D-fucopyranoside

Downstream raw materials:

1-(4-aminophenoxy)-α-L-rhamnopyranoside

p-nitrophenyl 2,3-O-isopropylidene-α-L-rhamnopyranoside

p-nitrophenyl 4-O-benzyl-α-L-rhamnopyranoside

p-nitrophenyl 4-O-benzyl-3-O-methyl-α-L-rhamnopyranoside