Decanenitrile, 4-oxo-

Base Information

• Chemical Name: Decanenitrile, 4-oxo-
• CAS No.: 73642-84-9
• Molecular Formula: C10H17NO
• Molecular Weight: 167.251
• Mol file: 73642-84-9.mol

Synonyms:

Chemical Property of Decanenitrile, 4-oxo-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Decanenitrile, 4-oxo-

There total 1 articles about Decanenitrile, 4-oxo- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

carbon monoxide (201230-82-2) + 1-Iodohexane (638-45-9) + acrylonitrile (107-13-1,25014-41-9) → nonanonitrile (2243-27-8) + 4-oxo-capronitrile (73642-84-9)

Guidance literature:

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In benzene; at 80 ℃; for 2h; under 60800 Torr;

DOI:10.1021/jo00017a001

Reference yield:

4-oxo-capronitrile (73642-84-9) → C19H27NO3

Guidance literature:

Multi-step reaction with 2 steps

1: L-(-)-glucose; bakers’ yeast ketoreductase / aq. phosphate buffer / 28 °C / pH 7.4 / Enzymatic reaction

2: dmap; dicyclohexyl-carbodiimide

With dmap; L-(-)-glucose; bakers’ yeast ketoreductase; dicyclohexyl-carbodiimide; In aq. phosphate buffer;

DOI:10.1055/s-0033-1339282

Reference yield:

4-oxo-capronitrile (73642-84-9) → (R)-5-Hexyl-dihydro-furan-2-one (107797-26-2,2825-92-5)

Guidance literature:

Multi-step reaction with 2 steps

1.1: L-(-)-glucose; bakers’ yeast ketoreductase / aq. phosphate buffer / 28 °C / pH 7.4 / Enzymatic reaction

2.1: water; dihydrogen peroxide; sodium hydroxide / 2 h / 70 °C

2.2: pH 2 - 3

With L-(-)-glucose; bakers’ yeast ketoreductase; water; dihydrogen peroxide; sodium hydroxide; In aq. phosphate buffer;

DOI:10.1055/s-0033-1339282

upstream raw materials:

carbon monoxide

1-Iodohexane

acrylonitrile

Downstream raw materials:

(R)-5-Hexyl-dihydro-furan-2-one