Technology Process of Cyclohexanecarboxylic acid, 1,3-dimethyl-, ethyl ester, cis-
There total 14 articles about Cyclohexanecarboxylic acid, 1,3-dimethyl-, ethyl ester, cis- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
lithium diisopropyl amide;
In
tetrahydrofuran; hexane;
at -78 ℃;
for 1h;
Yield given;
DOI:10.1139/v96-279
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 63 percent / LDA / tetrahydrofuran; hexane; hexamethylphosphoric acid triamide / -78 - -40 °C
2: 60 percent / n-butyllithium, DIBAL / tetrahydrofuran; toluene; hexane / -78 deg C; rt
3: 96 percent / H2 / 10percent Pd/C / ethanol
4: 100 percent / Et3N / CH2Cl2
5: 92 percent / LiBr / acetone / Heating
6: LDA / tetrahydrofuran; hexane / 1 h / -78 °C
With
n-butyllithium; hydrogen; diisobutylaluminium hydride; triethylamine; lithium bromide; lithium diisopropyl amide;
palladium on activated charcoal;
In
tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; ethanol; hexane; dichloromethane; acetone; toluene;
DOI:10.1139/v96-279
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 60 percent / n-butyllithium, DIBAL / tetrahydrofuran; toluene; hexane / -78 deg C; rt
2: 96 percent / H2 / 10percent Pd/C / ethanol
3: 100 percent / Et3N / CH2Cl2
4: 92 percent / LiBr / acetone / Heating
5: LDA / tetrahydrofuran; hexane / 1 h / -78 °C
With
n-butyllithium; hydrogen; diisobutylaluminium hydride; triethylamine; lithium bromide; lithium diisopropyl amide;
palladium on activated charcoal;
In
tetrahydrofuran; ethanol; hexane; dichloromethane; acetone; toluene;
DOI:10.1139/v96-279
