Succinamide

Base Information

• Chemical Name: Succinamide
• CAS No.: 110-14-5
• Molecular Formula: C4H8N2O2
• Molecular Weight: 116.12
• Hs Code.: 2924199090
• European Community (EC) Number: 203-739-9
• NSC Number: 8157
• UNII: Y656F4N881
• DSSTox Substance ID: DTXSID4059382
• Nikkaji Number: J127.778B
• Wikidata: Q27294303
• Metabolomics Workbench ID: 71489
• ChEMBL ID: CHEMBL541705
• Mol file: 110-14-5.mol

Synonyms:succinamide

Chemical Property of Succinamide

Chemical Property:

• Appearance/Colour: white to off-white fine crystalline powder
• Vapor Pressure: 6.7E-10mmHg at 25°C
• Melting Point: 260-265 °C (dec.)(lit.)
• Refractive Index: 1.488
• Boiling Point: 494 °C at 760 mmHg
• PKA: 15.88±0.40(Predicted)
• Flash Point: 252.6 °C
• PSA: 86.18000
• Density: 1.207 g/cm³
• LogP: 0.13780
• Storage Temp.: Store below +30°C.
• Solubility.: cold water: soluble220 part
• Water Solubility.: Slightly soluble in water.
• XLogP3: -2.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 116.058577502
• Heavy Atom Count: 8
• Complexity: 96.6

Purity/Quality:

99.5% ^*data from raw suppliers

Succinamide >98.0%(T) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 43
• Safety Statements: 36/37

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Other Classes -> Amides, Other
• Canonical SMILES: C(CC(=O)N)C(=O)N
• Uses: Succinamide has been used in the characterization of a novel biuret hydrolase from the cysteine hydrolase superfamily. It was used as nitrogen supplement in the culture medium of Scenedesmus obliquus and green algae.

Technology Process of Succinamide

There total 28 articles about Succinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

butanedinitrile (110-61-2) → butanediamide (110-14-5)

Guidance literature:

With manganese(IV) oxide; water; In isopropyl alcohol; at 100 ℃; for 0.5h; under 5171.62 Torr;

DOI:10.1021/ol403591c

Reference yield:

diammonium succinate (2226-88-2) → Succinimide (123-56-8,89963-74-6) + butanediamide (110-14-5) + succinamic acid (638-32-4)

Guidance literature:

In water; at 160 - 270 ℃; for 0.5 - 8h; Product distribution / selectivity;

Reference yield:

butanedinitrile (110-61-2) → 3-cyanopropionamide (61892-68-0) + butanediamide (110-14-5)

Guidance literature:

With basic ion exchanger; water;

upstream raw materials:

Succinimide

butanedinitrile

succinic acid

N,N'-bis-ethoxycarbonyl-succinamide

Downstream raw materials:

Succinimide

5,6-dhydrouracil

succinamic acid

urea

Refernces

• 1、 Sharghi, Hashem,Sarvari, Mona Hosseini. "A facile hydration of nitriles into amides by Al2O3/MeSO3H (AMA)". . p. 207 - 212. Retrieved 2003.
• 2、 Battilocchio, Claudio,Hawkins, Joel M.,Ley, Steven V.. "Mild and selective heterogeneous catalytic hydration of nitriles to amides by flowing through manganese dioxide". supporting information. p. 1060 - 1063. Retrieved 2016/10/17.
• 3、 -. "PROCESS FOR PRODUCING N-METHYL SUCCINIMIDE". Page 15; 16. . Retrieved 2008/06/13.