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Ammonium succinate is a chemical compound consisting of ammonium (NH4+) and succinate, which is the salt of succinic acid. It is a white, crystalline solid that is soluble in water and exhibits a slightly acidic pH. Known for its versatile chemical properties, ammonium succinate is utilized in a variety of applications across different industries.

2226-88-2

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2226-88-2 Usage

Uses

Used in Pharmaceutical Production:
Ammonium succinate is used as an excipient in the pharmaceutical industry for its buffering capacity and solubility properties, which aid in the formulation and stabilization of various medications.
Used as a Food Additive:
In the food industry, ammonium succinate is used as a flavor enhancer and a preservative due to its ability to improve taste and extend shelf life.
Used in Chemical Processes as a Buffering Agent:
Ammonium succinate serves as a buffering agent in chemical processes to maintain pH stability, which is crucial for the efficiency and safety of certain reactions.
Used as a Complexing Agent in Analytical Chemistry:
In analytical chemistry, ammonium succinate is employed as a complexing agent to facilitate the analysis of certain compounds, enhancing the accuracy and precision of measurements.
Used as a Precursor in Organic Synthesis:
Ammonium succinate is utilized as a precursor in the synthesis of other organic compounds, contributing to the creation of a wide range of chemical products.
Used in Fire-Retardant Applications:
Ammonium succinate has been studied for its potential use as a fire-retardant, leveraging its chemical properties to enhance safety in various materials and products.
Used as a Corrosion Inhibitor in Industrial Processes:
In industrial applications, ammonium succinate is used as a corrosion inhibitor to protect materials and equipment from degradation, extending their lifespan and improving operational efficiency.

Check Digit Verification of cas no

The CAS Registry Mumber 2226-88-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,2,2 and 6 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 2226-88:
(6*2)+(5*2)+(4*2)+(3*6)+(2*8)+(1*8)=72
72 % 10 = 2
So 2226-88-2 is a valid CAS Registry Number.
InChI:InChI=1/C4H6O4.2H3N/c5-3(6)1-2-4(7)8;;/h1-2H2,(H,5,6)(H,7,8);2*1H3

2226-88-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name AMMONIUM SUCCINATE

1.2 Other means of identification

Product number -
Other names succinic acid,ammonium succinate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only. Food Additives: FOOD_ADDITIVE
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:2226-88-2 SDS

2226-88-2Relevant academic research and scientific papers

Preparation method of organic metal salt additive (by machine translation)

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Paragraph 0013; 0025; 0029, (2020/06/02)

The organic metal salt additive, prepared by mixing :(1), washing, with short-chain organic acid as acid source, and then mixing, with the resulting solution of Step ;(2) to obtain the high-purity organic metal salt additive, has the advantages (1) as follows, The organic metal salt additive is relatively high in crystal form structure and high in purity, and has good industrial application prospects, through mixing, of an iron source or a calcium source, or a, zinc source with a high-purity, organic metal salt additive agent in an aqueous solution with, a wide,price. product source. (by machine translation)

A PROCESS FOR PREPARING SUCCINATE ESTER

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Paragraph 0079; 0089, (2016/11/07)

This invention relates to a process for preparing succinate ester from a succinic acid salt present in a fermentation broth. In the first stage of this invention, renewable carbon resources are utilized to produce succinic acid in the form of a succinic acid salt through biological fermentation. The succinic acid salt present in the fermentation broth is subjected to double displacement reaction with a strong acid leading to the release of succinic acid. Succinic acid is recovered by fractional crystallization integrated with an alcohol washing step and subjected to esterification reaction to produce succinate ester which is purified by fractional distillation. The succinate ester thus obtained is converted into 1,4-butanediol, gamma-butyrolactone and tetrahydrofuran through hydrogenation reactions. The succinate ester can also be hydrolyzed to yield highly pure succinic acid.

PROCESSES FOR PRODUCING CARBOXYLIC ACIDS FROM FERMANTATION BROTHS CONTAINING THEIR AMMONIUM SALTS

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Paragraph 0065-0068, (2013/03/28)

Process for the preparation of carboxylic acids like succinic acid (SA) from their correponding biologically-produced ammonium salts (like DAS) and / or amides and / or imides. The process involves reacting the biologically-produced derivatives at high temperature, removing ammonia and water, crystallizing the carboxylic acid obtained and recycling the mother liquor to the reaction system.

METHOD FOR PREPARING AMMONIUM SALTS OF FUMARIC OR SUCCINIC ACID

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Page/Page column 3, (2012/06/01)

An improved process for preparing ammonium salts from fumaric or succinic acid, is described. The method consists of neutralizing the corresponding acid carbonate or ammonium bicarbonate at a molar stoichiometric or greater than the stoichiometric ratio of 4-5% in a saturated aqueous solution of the synthesized salt at a temperature not exceeding 40° C., followed by separation of the product and drying at a temperature not exceeding 70° C. After separation of the ammonium salts, the filtrate can be re-used. Isolation of the product is usually carried out by cooling the reaction mixture to a temperature of 15-18C°. The product comes out in almost crystalline form. Saturated aqueous solution of the synthesized salt is formed by the interaction of carbonate or ammonium bicarbonate with the appropriate acid at a temperature not exceeding 40° C. It is possible to obtain cleaner salt concentration weighing more than 99% and not yielding lower than 98%. The method allows for an increase in the yield of targeted products and ensures their consistent high quality due to their formation in crystalline form.

PROCESSES FOR PRODUCING BUTANEDIOL AND DIAMINOBUTANE FROM FERMENTATION BROTHS CONTAINING AMMONIUM SUCCINATES

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Page/Page column 14-16, (2012/12/13)

Processes include providing a clarified diammonium succinate (DAS)- or monoammonium succinate (MAS)- containing fermentation broth; distilling the broth of an overhead that includes water and ammonia, and a liquid bottoms that includes SA, and at least about 20 wt% water; cooling the bottoms to a temperature sufficient to cause the bottoms to separate into a liquid portion in contact with a solid portion that is substantially pure SA; separating the solid portion from the liquid portion; and converting the solid portion to produce nitrogen containing compounds such as diamine butane (DAB), succinic dinitrile (SDN), succinic amino nitrile (SAN) or succinamide (DAM) and downstream products.

Method for producing pyrrolidones from succinates from fermentation broths

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Page/Page column 15-17, (2011/10/03)

The present invention relates to a process for preparing a compound II or a composition comprising the compound II to a composition comprising succinimide and to a composition prepared by the process according to the invention.

PROCESS FOR MANUFACTURING SUCCINIC ACID

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Page/Page column 15-17, (2011/09/15)

The present invention discloses a Process for the preparation of succinic acid comprising the steps of : a) providing an aqueous medium comprising magnesium succinate by fermentation, wherein a carbohydrate source is fermented by means of a micro-organism to form succinic acid, a magnesium base being added as neutralising agent during fermentation to provide the magnesium succinate; b) subjecting the aqueous medium comprising magnesium succinate to a crystallisation step and a salt exchange step to provide an aqueous solution comprising a monovalent succinate salt, wherein the salt exchange, which is performed either prior to or after crystallisation, comprises treating the magnesium succinate with a monovalent base to provide a magnesium base and the monovalent succinate salt; c) adjusting the concentration of the monovalent succinate salt in the aqueous solution to a value between 10 and 35 wt.%; d) subjecting the aqueous solution comprising the monovalent succinate salt to water-splitting electrodialysis, to produce a first solution comprising monovalent base and a second solution comprising succinic acid and monovalent succinate salt, the electrodialysis being carried out to a partial conversion of 40 to 95 mole%; e) separating the second solution comprising succinic acid and monovalent succinate salt into succinic acid and a solution comprising the monovalent succinate salt by crystallisation; f) recycling the solution of step e) comprising the monovalent succinate salt to step d).

Process for manufacturing succinic acid

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Page/Page column 6-7, (2011/09/15)

The present invention discloses a Process for the preparation of succinic acid comprising the steps of: a) providing an aqueous medium comprising magnesium succinate by fermentation, wherein a carbohydrate source is fermented by means of a micro-organism to form succinic acid, a magnesium base being added as neutralising agent during fermentation to provide the magnesium succinate; b) subjecting the aqueous medium comprising magnesium succinate to a crystallisation step and a salt exchange step to provide an aqueous solution comprising a monovalent succinate salt, wherein the salt exchange, which is performed either prior to or after crystallisation, comprises treating the magnesium succinate with a monovalent base to provide a magnesium base and the monovalent succinate salt; c) adjusting the concentration of the monovalent succinate salt in the aqueous solution to a value between 10 and 35 wt.%; d) subjecting the aqueous solution comprising the monovalent succinate salt to water-splitting electrodialysis, to produce a first solution comprising monovalent base and a second solution comprising succinic acid and monovalent succinate salt, the electrodialysis being carried out to a partial conversion of 40 to 95 mole%; e) separating the second solution comprising succinic acid and monovalent succinate salt into succinic acid and a solution comprising the monovalent succinate salt by crystallisation; f) recycling the solution of step e) comprising the monovalent succinate salt to step d).

PROCESSES FOR PRODUCING DIAMINOBUTANE (DAB), SUCCINIC DINITRILE (SDN) AND SUCCINAMIDE (DAM)

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Page/Page column 14-15, (2011/12/04)

Processes include providing a clarified diammonium succinate (DAS)- or monoammonium succinate (MAS)- containing fermentation broth; distilling the broth of an overhead that includes water and ammonia, and a liquid bottoms that includes SA, and at least about 20 wt% water; cooling the bottoms to a temperature sufficient to cause the bottoms to separate into a liquid portion in contact with a solid portion that is substantially pure SA; separating the solid portion from the liquid portion; and converting the solid portion to produce nitrogen containing compounds such as diamino butane (DAB), succinic dinitrile (SDN), succinic amino nitrile (SAN) or succinamide (DAM) and downstream products.

PROCESSES FOR THE PRODUCTION OF PYRROLIDONES

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Page/Page column 18-19, (2011/12/04)

Processes for making pyrrolidones include providing a clarified diammonium succinate (DAS)-containing and/or monoammonium succinate (MAS)-containing fermentation broth; distilling the broth under super atmospheric pressure at a temperature of greater than 100°C to about 300°C to form an overhead that includes water and ammonia, and a liquid bottoms that includes SA, and at least about 20 wt% water; cooling and/or evaporating the bottoms to attain a temperature and composition sufficient to cause the bottoms to separate into a liquid portion and a solid portion that is substantially pure SA; separating the solid portion from the liquid portion; and converting the solid SA portion to pyrrolidones.

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