Chemical Property of CID 9817450
Chemical Property:
- Appearance/Colour:White to pale-yellow crystalline solid
- Melting Point:300 ºC
- Boiling Point:557.6oC at 760 mmHg
- Flash Point:291oC
- PSA:101.31000
- LogP:-0.39430
- Storage Temp.:Refrigerator
- Solubility.:Aqueous Acid (Slightly)
- Hydrogen Bond Donor Count:2
- Hydrogen Bond Acceptor Count:6
- Rotatable Bond Count:5
- Exact Mass:288.020082
- Heavy Atom Count:17
- Complexity:254
- Purity/Quality:
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99% *data from raw suppliers
Polaprezinc *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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SDS file from LookChem
Useful:
- Canonical SMILES:C1=C(N=C[N-]1)CC(C(=O)[O-])NC(=O)CCN.[Zn+2]
- Isomeric SMILES:C1=C(N=C[N-]1)C[C@@H](C(=O)[O-])NC(=O)CCN.[Zn+2]
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Description
Polaprezinc, a complex of zinc ion and L-carnosine, is an antiulcer agent
launched in Japan. It is effective in promoting the healing of gastric ulcers in
addition to preventing ulcer relapse. In rat studies, polaprezinc reduces the
incidence of stomach lesions induced by ethanol. No effect was seen on
ultrastructural damage or on cell proliferation and it appears that polaprezinc
combines the cytoprotective effect of zinc with the ulcer healing properties of Lcarnosine.
The in vivo antioxidative properties of polaprezinc has been suggested
to be responsible for its protective effect against gastric mucosal injury. Recent studies revealed that polaprezinc is an activator of bone formetion and
has inhibitory effect of bone resorption. This agent is thus able to prevent the
deterioration of bone metabolism indicating its potential usefulness in the treatment
of osteoporosis. Polaprezinc has also been claimed for the prophylaxis and
treatment of alcoholic hepatopathy, viral hepatitis or other hepatopathies caused by
certain drugs, poisons and radiation.
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Uses
A novel anti-gastric ulcer agent PepZinGI(R) is a new dietary supplement approved by the federal agency. Don`t hesitate to contact us for more information. Attributes New dietary supplement Contact anti-ulcer drug, antioxidative,