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| CAS No.: | 107667-60-7 |
|---|---|
| Name: | Polaprezinc |
| Molecular Structure: | |
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| Formula: | C9H12N4O3Zn |
| Molecular Weight: | 289.609 |
| Synonyms: | Zinc,[N-b-alanyl-L-histidinato(2-)-N,NN,Oa]-;L-Histidine, N-b-alanyl-, zinc complex;Promac;Promac (antiulcer agent);Z 103;Zinc L-carnosine;b-Alanyl-L-histidinato zinc; |
| EINECS: | 600-848-7 |
| Melting Point: | 300 ºC |
| Boiling Point: | 557.6oC at 760 mmHg |
| Flash Point: | 291oC |
| Appearance: | White to pale-yellow crystalline solid |
| PSA: | 101.31000 |
| LogP: | -0.39430 |
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Chemistry
IUPAC Name: Zinc(2R)-2-[(3-amino-1-oxidopropylidene)amino]-3-(1H-imidazol-5-yl)propanoate
The MF of Polaprezinc (CAS NO.107667-60-7) is C9H12N4O3Zn.
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The MW of Polaprezinc (CAS NO.107667-60-7) is 289.62558.
Synonyms of Polaprezinc (CAS NO.107667-60-7): Histidine, beta-alanyl-, zinc salt ; zinc 2-(beta-Alanylamino)-3-(imidazol-3-id-4-yl)propanoate ; Zinc carnosine
Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals
Apperance: White To Pale-Yellow Crystalline Solid
Melting Point: >300 °C
Uses
Polaprezinc (CAS NO.107667-60-7) is used as A novel anti-gastric ulcer agent and a new dietary supplement approved by the federal agency.
Toxicity Data With Reference
| 1. | orl-rat LD50:7375 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 41 (1991),1033. | ||
| 2. | ipr-rat LD50:405 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 41 (1991),1033. | ||
| 3. | scu-rat LD50:>5 g/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 41 (1991),1033. | ||
| 4. | orl-mus LD50:1269 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 41 (1991),1033. | ||
| 5. | ipr-mus LD50:165 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 41 (1991),1033. | ||
| 6. | scu-mus LD50:758 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 41 (1991),1033. | ||
| 7. | orl-dog LD:>200 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 45 (1995),52. | ||
| 8. | orl-mky LD:>626 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 43 (1993),562. |
Safety Profile
A poison by intraperitoneal route. Moderately toxic by ingestion and subcutaneous routes. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic vapors of NOx and Zn.