Methyl 4-[5-(4-methoxycarbonylphenyl)-1,3,4-oxadiazol-2-yl]benzoate

Base Information

Chemical Name:Methyl 4-[5-(4-methoxycarbonylphenyl)-1,3,4-oxadiazol-2-yl]benzoate
CAS No.:7531-07-9
Molecular Formula:C₁₈H₁₄N₂O₅
Molecular Weight:338.32
Hs Code.:
DSSTox Substance ID:DTXSID70413380
Nikkaji Number:J935.050K
Wikidata:Q82221427

Synonyms:7531-07-9;Methyl 4-[5-(4-methoxycarbonylphenyl)-1,3,4-oxadiazol-2-yl]benzoate;Benzoic acid, 4,4'-(1,3,4-oxadiazole-2,5-diyl)bis-, dimethyl ester;2,5-bis(4-methoxycarbonylphenyl)-1,3,4-oxadiazole;dimethyl 4,4'-(1,3,4-oxadiazole-2,5-diyl)diphenylenedicarboxylate;DTXSID70413380;AJ-797/13833245;Dimethyl 4,4'-(1,3,4-oxadiazole-2,5-diyl)dibenzoate;methyl 4-{5-[4-(methoxycarbonyl)phenyl]-1,3,4-oxadiazol-2-yl}benzoate

Suppliers and Price of Methyl 4-[5-(4-methoxycarbonylphenyl)-1,3,4-oxadiazol-2-yl]benzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Methyl 4-[5-(4-methoxycarbonylphenyl)-1,3,4-oxadiazol-2-yl]benzoate

Chemical Property:

PSA：91.52000
LogP:2.97680
XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:6
Exact Mass:338.09027155
Heavy Atom Count:25
Complexity:428

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=CC=C(C=C1)C2=NN=C(O2)C3=CC=C(C=C3)C(=O)OC

Technology Process of Methyl 4-[5-(4-methoxycarbonylphenyl)-1,3,4-oxadiazol-2-yl]benzoate

There total 3 articles about Methyl 4-[5-(4-methoxycarbonylphenyl)-1,3,4-oxadiazol-2-yl]benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 120-61-6
1,4-benzenedicarboxylic acid dimethyl ester

: 7531-07-9
2,5-bis-(4-methoxycarbonylphenyl)-1,3,4,-oxadiazole

Guidance literature:: Multi-step reaction with 3 steps

1: hydrazine hydrate / methanol / 6 h / Heating

2: tetrahydrofuran; pyridine / 6 h / 20 °C

3: phosphoric acid chloride; DMF / 18 h / Heating

With hydrazine hydrate; N,N-dimethyl-formamide; trichlorophosphate; In tetrahydrofuran; pyridine; methanol;
DOI:10.1107/S0108270103021413

Reference yield:

: 13188-55-1
4-hydrazinocarbonylbenzoic acid methyl ester

: 7531-07-9
2,5-bis-(4-methoxycarbonylphenyl)-1,3,4,-oxadiazole

Guidance literature:: Multi-step reaction with 2 steps

1: tetrahydrofuran; pyridine / 6 h / 20 °C

2: phosphoric acid chloride; DMF / 18 h / Heating

With N,N-dimethyl-formamide; trichlorophosphate; In tetrahydrofuran; pyridine;
DOI:10.1107/S0108270103021413