1-Bromo-2-(2-chloroethyl)benzene

Base Information

Chemical Name:1-Bromo-2-(2-chloroethyl)benzene
CAS No.:75534-18-8
Molecular Formula:C8H8BrCl
Molecular Weight:219.509
Hs Code.:
European Community (EC) Number:857-594-7
Nikkaji Number:J1.835.006H

Synonyms:1-bromo-2-(2-chloroethyl)benzene;75534-18-8;2-bromophenethylchloride;SCHEMBL4965401;FFJNMAJBMVALKU-UHFFFAOYSA-N;AKOS014196897;CS-0237137;EN300-178419

Suppliers and Price of 1-Bromo-2-(2-chloroethyl)benzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 1-Bromo-2-(2-chloroethyl)benzene

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:0
Rotatable Bond Count:2
Exact Mass:217.94979
Heavy Atom Count:10
Complexity:95.3

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)CCCl)Br

Technology Process of 1-Bromo-2-(2-chloroethyl)benzene

There total 5 articles about 1-Bromo-2-(2-chloroethyl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 1074-16-4
2-bromophenylethyl alcohol

: 75534-18-8
1-bromo-2-(2-chloro-ethyl)benzene

Guidance literature:: 2-bromophenylethyl alcohol; With methanesulfonyl chloride; triethylamine; In toluene; at 0 ℃; for 1h;

With lithium chloride; In N,N-dimethyl-formamide; at 20 ℃; for 24h;
DOI:10.1016/S0022-328X(02)01473-0

Reference yield:

: 130089-19-9,130089-23-5,59436-11-2
1-bromo-2-(2-methoxyethenyl)benzene

: 75534-18-8
1-bromo-2-(2-chloro-ethyl)benzene

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogenchloride; water / tetrahydrofuran / 1.2 h / Inert atmosphere; Reflux

2: sodium tetrahydroborate / methanol / 0.67 h / 0 - 20 °C / Inert atmosphere

3: tetrachloromethane; triethylamine; triphenylphosphine / N,N-dimethyl-formamide / 3 h / 20 °C / Inert atmosphere

With hydrogenchloride; tetrachloromethane; sodium tetrahydroborate; water; triethylamine; triphenylphosphine; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.1002/anie.201108027

Reference yield:

: 96557-30-1
2-bromophenylacetaldehyde

: 75534-18-8
1-bromo-2-(2-chloro-ethyl)benzene

Guidance literature:: Multi-step reaction with 2 steps

1: sodium tetrahydroborate / methanol / 0.67 h / 0 - 20 °C / Inert atmosphere

2: tetrachloromethane; triethylamine; triphenylphosphine / N,N-dimethyl-formamide / 3 h / 20 °C / Inert atmosphere

With tetrachloromethane; sodium tetrahydroborate; triethylamine; triphenylphosphine; In methanol; N,N-dimethyl-formamide;
DOI:10.1002/anie.201108027