Aminobimane

Base Information

Chemical Name:Aminobimane
CAS No.:76421-90-4
Molecular Formula:C10H13N3O2
Molecular Weight:207.232
Hs Code.:
European Community (EC) Number:635-446-0
DSSTox Substance ID:DTXSID10443060
Nikkaji Number:J356.023F
Wikidata:Q82260754
Mol file:76421-90-4.mol

Synonyms:Aminobimane;Bimane amine;76421-90-4;7-(aminomethyl)-1,2,6-trimethylpyrazolo[1,2-a]pyrazole-3,5-dione;SCHEMBL13483460;DTXSID10443060;2,5,6-Trimethyl-3-(aminomethyl)-1H,7H-pyrazolo[1,2-a]pyrazole-1,7-dione;Bimane amine, BioReagent, suitable for fluorescence, >=98.0% (HPCE)

Suppliers and Price of Aminobimane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
Bimane amine BioReagent, suitable for fluorescence, ≥98.0% (HPCE)
5mg
$ 461.00

American Custom Chemicals Corporation
3-AMINOMETHYL-2,5,6-TRIMETHYL-1H,7H-PYRAZOLO[1,2-A]PYRAZOLE-1,7-DIONE 95.00%
5MG
$ 495.54

Total 4 raw suppliers

Chemical Property of Aminobimane

Chemical Property:

PSA：68.98000
LogP:0.28120
Storage Temp.:?20°C
XLogP3:-0.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:207.100776666
Heavy Atom Count:15
Complexity:434

Purity/Quality:

98%,99%, ^*data from raw suppliers

Bimane amine BioReagent, suitable for fluorescence, ≥98.0% (HPCE) ^*data from reagent suppliers

Safty Information:

Pictogram(s): 4186574
Hazard Codes:T
Statements: 25
Safety Statements: 45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(N2C(=C(C(=O)N2C1=O)C)CN)C
Uses Bimane amine (Aminobimane) may be useful as a fluorescent probe for molecules that react with primary amines.

Technology Process of Aminobimane

There total 4 articles about Aminobimane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 4.0%

: 71418-44-5
monobromobimane

: 76421-90-4
9,10-dioxa-syn-(aminomethyl,methyl)(methyl,methyl)bimane

: 76421-91-5
9,10-dioxa-syn-(cyano,methyl)(methyl,methyl)bimane

Guidance literature:: With ammonium hydroxide; In acetonitrile; for 3h;
DOI:10.1021/jo00321a029

Reference yield:

: 9,10-dioxa-syn-(glycyl-tryptophyl-aminomethyl,methyl)(methyl,methyl)bimane p-toluenesulfonic acid

: 76421-90-4
9,10-dioxa-syn-(aminomethyl,methyl)(methyl,methyl)bimane

: 2390-74-1
N-glycyl-L-tryptophan

Guidance literature:: With mercaptoethylamine hydrochloride; water; cathepsin C from bovine spleen; In dimethyl sulfoxide; at 37 ℃; Rate constant; fluorometric enzyme essay;
DOI:10.1248/cpb.38.2043

Reference yield:

: 76421-69-7
3-(hydroxymethyl)-2,5,6-trimethylpyrazolo[1,2-a]pyrazole-1,7-dione

: 76421-90-4
9,10-dioxa-syn-(aminomethyl,methyl)(methyl,methyl)bimane

Guidance literature:: Multi-step reaction with 2 steps

1: 39 percent / PBr₃ / CH₂Cl₂

2: 45 percent / aq. NH₃ / acetonitrile / 3 h

With ammonium hydroxide; phosphorus tribromide; In dichloromethane; acetonitrile;
DOI:10.1021/jo00321a029