3-(hydroxymethyl)-2,5,6-trimethylpyrazolo[1,2-a]pyrazole-1,7-dione

Base Information

• Chemical Name: 3-(hydroxymethyl)-2,5,6-trimethylpyrazolo[1,2-a]pyrazole-1,7-dione
• CAS No.: 76421-69-7
• Molecular Formula: C₁₀H₁₂N₂O₃
• Molecular Weight: 208.217
• Mol file: 76421-69-7.mol

Synonyms:3-(hydroxymethyl)-2,5,6-trimethylpyrazolo[1,2-a]pyrazole-1,7-dione

Chemical Property of 3-(hydroxymethyl)-2,5,6-trimethylpyrazolo[1,2-a]pyrazole-1,7-dione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-(hydroxymethyl)-2,5,6-trimethylpyrazolo[1,2-a]pyrazole-1,7-dione

There total 1 articles about 3-(hydroxymethyl)-2,5,6-trimethylpyrazolo[1,2-a]pyrazole-1,7-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

9,10-dioxa-syn-(glycyl-tryptophyloxymethyl,methyl)(methyl,methyl)bimane hydrochloride → 3-(hydroxymethyl)-2,5,6-trimethylpyrazolo[1,2-a]pyrazole-1,7-dione (76421-69-7) + N-glycyl-L-tryptophan (2390-74-1)

Guidance literature:

With mercaptoethylamine hydrochloride; water; cathepsin C from bovine spleen; In dimethyl sulfoxide; at 37 ℃; Rate constant; fluorometric enzyme assay;

DOI:10.1248/cpb.38.2043

Reference yield: 64.0%

3-(hydroxymethyl)-2,5,6-trimethylpyrazolo[1,2-a]pyrazole-1,7-dione (76421-69-7) → Monochlorobimane (76421-73-3)

Guidance literature:

With thionyl chloride; Heating;

DOI:10.1021/jo00321a029

Reference yield: 39.0%

3-(hydroxymethyl)-2,5,6-trimethylpyrazolo[1,2-a]pyrazole-1,7-dione (76421-69-7) → monobromobimane (71418-44-5)

Guidance literature:

With phosphorus tribromide; In dichloromethane;

DOI:10.1021/jo00321a029

Downstream raw materials:

monobromobimane

Monochlorobimane

9,10-dioxa-syn-(aminomethyl,methyl)(methyl,methyl)bimane