4-Chloro-3-isopropoxyaniline

Base Information

Chemical Name:4-Chloro-3-isopropoxyaniline
CAS No.:76464-54-5
Molecular Formula:C9H12ClNO
Molecular Weight:185.653
Hs Code.:
DSSTox Substance ID:DTXSID20512216
Wikidata:Q82371374

Synonyms:4-Chloro-3-isopropoxyaniline;76464-54-5;4-chloro-3-propan-2-yloxyaniline;SCHEMBL2372500;DTXSID20512216;QRZBEHUXMWTNTE-UHFFFAOYSA-N;BDA46454;MFCD19624982;AKOS013324327;4-Chloro-3-[(propan-2-yl)oxy]aniline;BS-25968;CS-0455625

Suppliers and Price of 4-Chloro-3-isopropoxyaniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 4-Chloro-3-isopropoxyaniline

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:185.0607417
Heavy Atom Count:12
Complexity:141

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)OC1=C(C=CC(=C1)N)Cl

Technology Process of 4-Chloro-3-isopropoxyaniline

There total 4 articles about 4-Chloro-3-isopropoxyaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 6358-06-1
5-amino-2-chlorophenol

: 75-26-3
isopropyl bromide

: 76464-54-5
4-chloro-3-isopropoxyaniline

Guidance literature:: With potassium carbonate; In acetonitrile; Reflux;

Reference yield:

: N-(4-chloro-3-isopropoxyphenyl)acetamide

: 76464-54-5
4-chloro-3-isopropoxyaniline

Guidance literature:: With ethanol; potassium hydroxide; In water; for 8h; Reflux;
DOI:10.1021/jm200015a

Reference yield:

: 6358-06-1
5-amino-2-chlorophenol

: 76464-54-5
4-chloro-3-isopropoxyaniline

Guidance literature:: Multi-step reaction with 3 steps

1: acetic acid / 0.08 h / Reflux

2: caesium carbonate / N,N-dimethyl-formamide / 18 h / Reflux

3: ethanol; potassium hydroxide / water / 8 h / Reflux

With ethanol; caesium carbonate; acetic acid; potassium hydroxide; In water; N,N-dimethyl-formamide;
DOI:10.1021/jm200015a