4,6-Dimethyl-2-benzofurancarboxylic acid

Base Information

Chemical Name:4,6-Dimethyl-2-benzofurancarboxylic acid
CAS No.:77037-40-2
Molecular Formula:C11H10O3
Molecular Weight:190.199
Hs Code.:
European Community (EC) Number:815-149-4
DSSTox Substance ID:DTXSID901274001
Nikkaji Number:J3.256.368F

Synonyms:77037-40-2;4,6-dimethylbenzofuran-2-carboxylic acid;4,6-Dimethyl-2-benzofurancarboxylic acid;4,6-dimethyl-1-benzofuran-2-carboxylic acid;SCHEMBL11743352;DTXSID901274001;4,6-dimethylbenzofuran-2-carboxylicacid;CS-0435031

Suppliers and Price of 4,6-Dimethyl-2-benzofurancarboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 19 raw suppliers

Chemical Property of 4,6-Dimethyl-2-benzofurancarboxylic acid

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:190.062994177
Heavy Atom Count:14
Complexity:239

Purity/Quality:: 99.9% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C2C=C(OC2=C1)C(=O)O)C

Technology Process of 4,6-Dimethyl-2-benzofurancarboxylic acid

There total 8 articles about 4,6-Dimethyl-2-benzofurancarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.9%

: 1666-02-0
2-hydroxy-4,6-dimethylbenzaldehyde

: 105-36-2
ethyl bromoacetate

: 77037-40-2
4,6-dimethyl-1-benzofuran-2-carboxylic acid

Guidance literature:: 2-hydroxy-4,6-dimethylbenzaldehyde; ethyl bromoacetate; With potassium carbonate; In N,N-dimethyl acetamide; at 80 - 130 ℃; for 2.5h; Inert atmosphere;

With ethanol; potassium hydroxide; at 80 ℃; for 1h;

Reference yield: 78.0%

: 1432644-46-6
ethyl (2-formyl-3,5-dimethylphenoxy)acetate

: 77037-40-2
4,6-dimethyl-1-benzofuran-2-carboxylic acid

Guidance literature:: ethyl (2-formyl-3,5-dimethylphenoxy)acetate; With ethanol; sodium ethanolate; at 20 - 70 ℃; for 1h;

With sodium hydroxide; at 20 - 70 ℃; for 0.333333h;
DOI:10.1021/jm4003878