2-anilino-N-phenyl-2-sulfanylideneacetamide

Base Information

• Chemical Name: 2-anilino-N-phenyl-2-sulfanylideneacetamide
• CAS No.: 78121-70-7
• Molecular Formula: C14H12N2OS
• Molecular Weight: 256.328
• DSSTox Substance ID: DTXSID00350754
• Nikkaji Number: J1.233.276I
• Wikidata: Q82126851
• Mol file: 78121-70-7.mol

Synonyms:2-anilino-N-phenyl-2-sulfanylideneacetamide;78121-70-7;N-phenyl-2-(phenylamino)-2-thioxoacetamide;TimTec1_000030;ST003159;n,n'-diphenylthiooxamide;Oprea1_084897;SCHEMBL3070810;DTXSID00350754;N^s^,N^o^-diphenyl(thiooxamide);HMS1534B08;AKOS003245191;NCGC00175542-01;BRD-K31105448-001-01-3

Chemical Property of 2-anilino-N-phenyl-2-sulfanylideneacetamide

Chemical Property:

• PSA: 73.22000
• LogP: 3.21060
• XLogP3: 3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 256.06703418
• Heavy Atom Count: 18
• Complexity: 294

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)NC(=O)C(=S)NC2=CC=CC=C2

Technology Process of 2-anilino-N-phenyl-2-sulfanylideneacetamide

There total 20 articles about 2-anilino-N-phenyl-2-sulfanylideneacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 32.0%

bis(phenylimidoyl)chloride (20033-74-3) + ethyl 2-sulfanylacetate (623-51-8) → N,N'-diphenylthiooxamide (78121-70-7) + ethyl 4-phenylamino-3-phenylimino-1,2-dithia-3H-cyclopent-4-ene-5-carboxylate

Guidance literature:

With N,N,N,N,-tetramethylethylenediamine; lithium diisopropyl amide; In tetrahydrofuran; at -78 - 20 ℃; for 16h;

DOI:10.1021/jo052450l

Reference yield:

2-anilino-N,N'-diphenyl-acetamidine (14181-81-8) → N,N'-Diphenyloxamid (620-81-5) + N,N'-diphenylthiooxamide (78121-70-7) + anilino-acetaldehyde phenylimine

Guidance literature:

at 150 ℃; Produkt 5: Dithiooxanilid;

DOI:10.1080/01944360008976123

Reference yield:

N,N'-diphenyldithiooxamide (6244-74-2) + acetone (67-64-1) → N,N'-Diphenyloxamid (620-81-5) + N,N'-diphenylthiooxamide (78121-70-7)

Guidance literature:

upstream raw materials:

N,N'-Diphenyloxamid

N,N'-diphenyldithiooxamide

N-phenyl-mercaptoacetamide disulfide

ethyl 2-amino-2-thioxoacetate

Downstream raw materials:

indole-2,3-dione

N,N'-Diphenyloxamid

N-phenylbenzo[d]thiazole-2-carboxamide

N,N'-diphenyldithiooxamide