Pyridine, 2-hexyl-5-(4-iodophenyl)-

Base Information

• Chemical Name: Pyridine, 2-hexyl-5-(4-iodophenyl)-
• CAS No.: 78313-75-4
• Molecular Formula: C₁₇H₂₀IN
• Molecular Weight: 365.257
• Mol file: 78313-75-4.mol

Synonyms:

Chemical Property of Pyridine, 2-hexyl-5-(4-iodophenyl)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Pyridine, 2-hexyl-5-(4-iodophenyl)-

There total 6 articles about Pyridine, 2-hexyl-5-(4-iodophenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 31.0%

2-hexyl-5-phenylpyridine (78313-71-0) → 2-hexyl-5-(p-iodophenyl)pyridine (78313-75-4)

Guidance literature:

With iodine; silver sulfate; In sulfuric acid; Ambient temperature;

DOI:10.1007/BF00507095

Reference yield:

2-(2-ethyl-5-thienyl)-5-phenylpyridine (78313-68-5) → 2-hexyl-5-(p-iodophenyl)pyridine (78313-75-4)

Guidance literature:

Multi-step reaction with 2 steps

1: Raney Ni / methanol

2: iodine, Ag₂SO₄, H₂SO₄

With sulfuric acid; iodine; silver sulfate; nickel; In methanol;

Reference yield:

1-(5-ethyl-thiophen-2-yl)-ethanone (18761-46-1) → 2-hexyl-5-(p-iodophenyl)pyridine (78313-75-4)

Guidance literature:

Multi-step reaction with 5 steps

1: 3M sodium methoxide / pyridine

2: 1. 10percent aq. HCl; 2. 70percent HClO₄ / 1. methanol; 2. glacial acetic acid

3: 42 percent / ammonium acetate / acetic acid / Heating

4: 56 percent / Raney Ni / methanol / Heating

5: 31 percent / I₂, Ag₂SO₄ / aq. H₂SO₄ / Ambient temperature

With ammonium acetate; hydrogenchloride; perchloric acid; iodine; sodium methylate; nickel; silver sulfate; In pyridine; methanol; sulfuric acid; acetic acid;

DOI:10.1007/BF00507095

upstream raw materials:

2-hexyl-5-phenylpyridine

2-(2-ethyl-5-thienyl)-5-phenylpyridine

1-(5-ethyl-thiophen-2-yl)-ethanone

((Z)-3-Dimethylamino-2-phenyl-allylidene)-dimethyl-ammonium; perchlorate

Downstream raw materials:

2-hexyl-5-(-p-cyanophenyl)pyridine

Refernces

• 1、 Karamysheva, L.A.,Kovshev, E.I.,Pavluchenko, A.I.,Roitman, K.V.,Titov, V.V.,et al.. "New Heterocyclic Liquid Crystalline Compounds". . p. 241 - 252. Retrieved 2007/10/02.