18761-46-1

Usage

Appearance

Yellow to brown liquid

Usage

Pharmaceutical and chemical industries

Role

Intermediate in the synthesis of various organic compounds

Odor

Distinctive

Applications

Building block in the production of medicines, flavor and fragrance additives, and other specialty chemicals

Safety Precautions

Handle and store with caution

Hazardous Nature

Flammable and potentially hazardous if not properly handled

InChI:InChI=1/C8H10OS/c1-3-7-4-5-8(10-7)6(2)9/h4-5H,3H2,1-2H3

Upstream product

• 872-55-9 2-ethylthiophene 
• 108-24-7 acetic anhydride 
• 75-36-5 acetyl chloride 
• 62323-44-8 2-bromo-5-ethylthiophene 
• 64964-17-6 5-Ethyl-2-thiophencarbonsaeurechlorid 
• 506-82-1 dimethylcadmium 
• 88-15-3 2-Acetylthiophene 

Downstream Products

• 111-13-7 hexyl-methyl-ketone 
• 917873-75-7 1-(4-bromo-5-ethyl-thiophen-2-yl)-3-(4-hydroxy-3,5-dimethyl-phenyl)-propan-1-one 
• 78313-75-4 2-hexyl-5-(p-iodophenyl)pyridine 
• 78313-68-5 2-(2-ethyl-5-thienyl)-5-phenylpyridine 
• 78313-79-8 2-hexyl-5-(-p-cyanophenyl)pyridine 
• 78313-76-5 2-hexyl-5-(p-bromophenyl)pyridine 
• 78313-71-0 2-hexyl-5-phenylpyridine 
• 4282-31-9 Thiophene-2,5-dicarboxylic acid 
• 40477-61-0 5-ethyl-4-bromo-thiophene-2-carboxylic acid 
• 23229-72-3 5-ethyl-2-thiophenecarboxylic acid 
• 5069-23-8 2,5-diethyl-thiophene 
• 18761-51-8 2,5,2',5'-tetraethyl-[3,3']bithiophenyl 

Relevant academic research and scientific papers

Novel iron and gallium salts of Aquivion PFSA: Synthesis, characterization and some catalytic applications

The objective of this study was to prepare, characterize and test the catalytic properties of iron and gallium salts of Aquivion PFSA (hereinafter Aquivion-H). The samples were characterized by the determination of metal loading in fresh and used materials, ATR-FTIR, and thermogravimetric analysis (TG-DSC). The salts were screened in Friedel-Crafts acylation of some heterocyclic compounds and compared with some homogeneous and heterogeneous Lewis acids as well as with pure Aquivion-H. These new salts revealed efficient catalytic activity and recyclability.

Facile preparation of 5-alkyl-1-aryltetrazoles with arenes, acyl chlorides, hydroxylamine, and diphenylphosphoryl azide

Successive treatment of arenes with acyl chlorides and AlCl3, the addition of water and removal of solvent, the reaction with NH2OH?HCl and K2CO3, and the reaction with diphenylphosphoryl azide and DBU under warming conditions gave the corresponding 5-alkyl-1-aryltetrazoles efficiently in good to moderate yields. The present method is one-pot transformation of arenes into 5-alkyl-1-aryltetrazoles using the Friedel-Crafts acylation and the Beckmann rearrangement under transition-metal-free conditions.

CYCLIC SULFAMIDE COMPOUNDS AND METHODS OF USING SAME

The present disclosure provides, in part, cyclic sulfamide compounds, and pharmaceutical compositions thereof, useful as modulators of Hepatitis B (HBV) core protein, and methods of treating Hepatitis B (HBV) infection.

Thiophen-2-yl and bithienyl substituted pyrazine-2,3-dicarbonitriles as precursors for tetrasubstituted zinc azaphthalocyanines

Peripheral thiophen-2-yl substituents extend the macrocyclic conjugation of zinc(II)azaphthalocyanines, (ZnAzaPc), due to coplanarity between the two ring systems, and red-shifted UV-Vis Q-bands are observed. This lowering in energy is favourable for vari

NOVEL 4-HETEROARYLIMIDAZOLE-2-THIONE TYROSINASE INHIBITORS AND PHARMACEUTICAL/COSMETIC APPLICATIONS THEREOF

Novel 4-heteroarylimidazole-2-thione tyrosinase inhibiting compounds corresponding to the following general formula (I): formulated into pharmaceutical or cosmetic compositions are useful for the treatment or prevention of pigmentary disorders, or for preventing and/or treating signs of skin aging, and/or for body or hair hygiene.

NOVEL THIOPHENE DERIVATIVES

The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.

Kinetics of the Detritiation of a Series of 4- and 5-Substituted 2-(acetyl)thiophenes

A series of 4- and 5-substituted 2-(acetyl)thiophenes have been prepared and the kinetics of the hydroxide-catalysed detritiation studied at 25.0 deg C.The second-order detritiation rate constants parallel those observed for the corresponding meta- and para-substituted acetophenones but as the reaction constant ρ is higher (1.61) the range of reactivity is much wider than that witnessed for the acetophenones.