2-dicyanomethylidene-2,3,4,5-tetrahydro-1H,6H-pyridine

Base Information

Chemical Name:2-dicyanomethylidene-2,3,4,5-tetrahydro-1H,6H-pyridine
CAS No.:78807-02-0
Molecular Formula:C8H9N3
Molecular Weight:147.18
Hs Code.:
DSSTox Substance ID:DTXSID90513139
Nikkaji Number:J433.125G
Wikidata:Q82372766

Synonyms:78807-02-0;2-piperidin-2-ylidenepropanedinitrile;2-dicyanomethylidene-2,3,4,5-tetrahydro-1H,6H-pyridine;SCHEMBL6822954;DTXSID90513139;2-dicyanomethylidenetetrahydropyridine;(Piperidin-2-ylidene)propanedinitrile;AKOS006349761

Suppliers and Price of 2-dicyanomethylidene-2,3,4,5-tetrahydro-1H,6H-pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-dicyanomethylidene-2,3,4,5-tetrahydro-1H,6H-pyridine

Chemical Property:

XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:147.079647300
Heavy Atom Count:11
Complexity:252

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCNC(=C(C#N)C#N)C1

Technology Process of 2-dicyanomethylidene-2,3,4,5-tetrahydro-1H,6H-pyridine

There total 1 articles about 2-dicyanomethylidene-2,3,4,5-tetrahydro-1H,6H-pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 5693-62-9
2,3,4,5-tetrahydro-6-methoxypyridine

: 109-77-3
malononitrile

: 78807-02-0
2-dicyanomethylidene-2,3,4,5-tetrahydro-1H,6H-pyridine

Guidance literature:: In ethanol; at 20 ℃; for 1h;
DOI:10.1007/BF00503561

Reference yield: 54.0%

: 78807-02-0
2-dicyanomethylidene-2,3,4,5-tetrahydro-1H,6H-pyridine

: 26226-72-2
4-[(chloroacetyl)amino]-benzoic acid, ethyl ester

: ethyl 4-(2-amino-1-cyano-5,6,7,8-tetrahydroindolizine-3-carboxamido)benzoate

Guidance literature:: With potassium carbonate; In acetone; at 50 - 60 ℃; for 24h;
DOI:10.1016/j.bioorg.2019.103371

Reference yield:

: 78807-02-0
2-dicyanomethylidene-2,3,4,5-tetrahydro-1H,6H-pyridine

: 10-Methyl-4,9-dioxo-3,4b,5,6,7,8,9,10-octahydro-4H-1,3,8a,10-tetraaza-phenanthrene-2-carboxylic acid cyclohexylamide

Guidance literature:: Multi-step reaction with 5 steps

2: NaBH₄ / ethanol

3: 96.5 percent / benzene / 3 h / Ambient temperature

4: 2 h / Heating

5: ethanol / 4 h / Heating

With sodium tetrahydroborate; In ethanol; benzene;
DOI:10.1016/0223-5234(96)88265-1