2-Bromo-3-methylpyridin-4-amine

Base Information

• Chemical Name: 2-Bromo-3-methylpyridin-4-amine
• CAS No.: 79055-61-1
• Molecular Formula: C₆H₇BrN₂
• Molecular Weight: 187.039
• Hs Code.: 2933399090
• DSSTox Substance ID: DTXSID90505453
• Wikidata: Q82360594
• Mol file: 79055-61-1.mol

Synonyms:2-Bromo-3-methylpyridin-4-amine;79055-61-1;2-Bromo-3-methyl-4-pyridinamine;SCHEMBL3402878;DTXSID90505453;2-Bromo-3-methylpyridin-4-ylamine;MFCD20720063;AKOS016002338;SB54548;DS-16097;CS-0106174;D82531;EN300-213034;A864937;J-508235

Chemical Property of 2-Bromo-3-methylpyridin-4-amine

Chemical Property:

• Melting Point: 121 °C(Solv: benzene (71-43-2))
• Boiling Point: 328.2±37.0 °C(Predicted)
• PKA: 5.26±0.42(Predicted)
• PSA: 38.91000
• Density: 1.593±0.06 g/cm3(Predicted)
• LogP: 2.31590
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 185.97926
• Heavy Atom Count: 9
• Complexity: 97.1

Purity/Quality:

97% ^*data from raw suppliers

2-Bromo-3-methylpyridin-4-amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C=CN=C1Br)N

Technology Process of 2-Bromo-3-methylpyridin-4-amine

There total 5 articles about 2-Bromo-3-methylpyridin-4-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

2-bromo-3-methyl-4-nitropyridine N-oxide (60323-97-9) → 4-amino-2-bromo-3-methylpyridine (79055-61-1)

Guidance literature:

With iron; ammonium chloride; In ethanol; water; at 90 ℃; for 6h;

Reference yield: 16.0%

2-bromo-3-methylpyridine 1-oxide (19230-57-0) → 6-amino-2-bromo-3-methylpyridine (89466-17-1) + 4-amino-2-bromo-3-methylpyridine (79055-61-1)

Guidance literature:

2-bromo-3-methylpyridine 1-oxide; With pyridine; trifluoromethylsulfonic anhydride; In acetonitrile; at 80 ℃; for 1h;

With ethanolamine; In acetonitrile; at 10 - 20 ℃; for 3h; Time;

Reference yield:

2-bromo-3-picoline (3430-17-9) → 4-amino-2-bromo-3-methylpyridine (79055-61-1)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 12 h / 20 °C

2.1: pyridine; trifluoromethylsulfonic anhydride / acetonitrile / 1 h / 80 °C

2.2: 3 h / 10 - 20 °C

With pyridine; trifluoromethylsulfonic anhydride; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; acetonitrile;

upstream raw materials:

2-bromo-3-methylpyridine 1-oxide

2-bromo-3-picoline

2-bromo-3-methyl-4-nitropyridine N-oxide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 79055-61-1 2-BroMo-3-Methyl-4-pyridinaMine

Send

Send

Metric Ton KG G Pound L ML

Send

Send