Methyl 3-(aminomethyl)thiophene-2-carboxylate

Base Information

Chemical Name:Methyl 3-(aminomethyl)thiophene-2-carboxylate
CAS No.:79472-21-2
Molecular Formula:C₇H₉NO₂S
Molecular Weight:171.22
Hs Code.:2934999090
Mol file:79472-21-2.mol

Synonyms:METHYL 3-(AMINOMETHYL)THIOPHENE-2-CARBOXYLATE;SCHEMBL160615;3-Aminomethyl-thiophene-2-carboxylic acid methyl ester;MMWQALKHHPSNNY-UHFFFAOYSA-N;EN300-1703170

Suppliers and Price of Methyl 3-(aminomethyl)thiophene-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Arctom
Methyl3-(aminomethyl)thiophene-2-carboxylatehydrochloride 97%
1g
$ 549.00

Total 4 raw suppliers

Chemical Property of Methyl 3-(aminomethyl)thiophene-2-carboxylate

Chemical Property:

PSA：80.56000
LogP:2.49570
XLogP3:0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:171.03539970
Heavy Atom Count:11
Complexity:151

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Methyl3-(aminomethyl)thiophene-2-carboxylatehydrochloride 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=C(C=CS1)CN

Technology Process of Methyl 3-(aminomethyl)thiophene-2-carboxylate

There total 4 articles about Methyl 3-(aminomethyl)thiophene-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 59961-15-8
methyl 3-(bromomethyl)thiophene-2-carboxylate

: 79472-21-2
3-(aminomethyl)thiophene-2-carboxylic acid methyl ester

Guidance literature:: With ammonia; In methanol; at 20 ℃; for 2h;

Reference yield:

: 81452-54-2
methyl 3-methylthiophene-2-carboxylate

: 79472-21-2
3-(aminomethyl)thiophene-2-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: NBS, dibenzoylperoxide / CCl₄ / Heating

2: NH₃ / dimethylformamide

With N-Bromosuccinimide; ammonia; dibenzoyl peroxide; In tetrachloromethane; N,N-dimethyl-formamide;
DOI:10.1016/S0960-894X(97)00348-X

Reference yield:

: 23806-24-8
3-methyl-2-thiophenecarboxylic acid

: 79472-21-2
3-(aminomethyl)thiophene-2-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: H₂SO₄ / Heating

2: NBS, dibenzoylperoxide / CCl₄ / Heating

3: NH₃ / dimethylformamide

With N-Bromosuccinimide; sulfuric acid; ammonia; dibenzoyl peroxide; In tetrachloromethane; N,N-dimethyl-formamide;
DOI:10.1016/S0960-894X(97)00348-X