METHYL 3-METHYLTHIOPHENE-2-CARBOXYLATE

Base Information

• Chemical Name: METHYL 3-METHYLTHIOPHENE-2-CARBOXYLATE
• CAS No.: 81452-54-2
• Molecular Formula: C7H8O2S
• Molecular Weight: 156.205
• Hs Code.: 29151300
• Mol file: 81452-54-2.mol

Synonyms:Methyl 3-methylthienyl-2-carboxylate;3-Methylthiophene-2-carboxylicacid methyl ester;Methyl 3-methyl-2-thiophenecarboxylate;

Chemical Property of METHYL 3-METHYLTHIOPHENE-2-CARBOXYLATE

Chemical Property:

• Vapor Pressure: 0.186mmHg at 25°C
• Refractive Index: 1.5168
• Boiling Point: 211 °C at 760 mmHg
• Flash Point: 81.4 °C
• PSA: 54.54000
• Density: 1.173 g/cm³
• LogP: 1.84310
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

Methyl 3-Methylthiophene-2-carboxylate ^*data from reagent suppliers

Safty Information:

• Safety Statements: 23-24/25

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of METHYL 3-METHYLTHIOPHENE-2-CARBOXYLATE

There total 19 articles about METHYL 3-METHYLTHIOPHENE-2-CARBOXYLATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methanol (67-56-1) + 3-methylthenoyl chloride (61341-26-2) → methyl 3-methylthiophene-2-carboxylate (81452-54-2)

Guidance literature:

for 18h; Reflux;

Reference yield: 97.0%

methanol (67-56-1) + 3-methyl-2-thiophenecarboxylic acid (23806-24-8) → methyl 3-methylthiophene-2-carboxylate (81452-54-2)

Guidance literature:

With sulfuric acid; for 12h; Reflux;

Reference yield: 95.6%

3-methyl-2-thiophenecarboxylic acid (23806-24-8) + dimethyl sulfate (77-78-1) → methyl 3-methylthiophene-2-carboxylate (81452-54-2)

Guidance literature:

With potassium carbonate; In acetone; at 25 - 30 ℃; for 4h;

upstream raw materials:

diazomethane

3-methyl-2-thiophenecarboxylic acid

2-iodo-3-methylthiophene

carbonic acid dimethyl ester

Downstream raw materials:

methyl 4-bromo-3-methylthiophene-2-carboxylate

methyl 4,5-dibromo-3-methylthiophene-2-carboxylate

3-methyl-4,5-dichlorothiophene-2-carboxylic acid

methyl 3-(bromomethyl)thiophene-2-carboxylate