tert-Butyl 2-(pyridin-4-yl)acetate

Base Information

Chemical Name:tert-Butyl 2-(pyridin-4-yl)acetate
CAS No.:79757-20-3
Molecular Formula:C11H15NO2
Molecular Weight:193.246
Hs Code.:2933399090
DSSTox Substance ID:DTXSID00459771
Nikkaji Number:J1.953.328J
Wikidata:Q82283618
Mol file:79757-20-3.mol

Synonyms:tert-Butyl 2-(pyridin-4-yl)acetate;79757-20-3;Tert-butyl 2-pyridin-4-ylacetate;Pyridin-4-yl-acetic acid tert-butyl ester;pyridin-4-ylacetic acid tert-butyl ester;DTXSID00459771;tert-Butyl2-(pyridin-4-yl)acetate;MFCD22565620;AKOS018720371;SB53238;AS-54952;CS-0455896;W11474

Suppliers and Price of tert-Butyl 2-(pyridin-4-yl)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
tert-Butyl2-(Pyridin-4-yl)acetate
10mg
$ 45.00

Crysdot
tert-Butyl2-(pyridin-4-yl)acetate 95+%
5g
$ 628.00

Chemenu
tert-butyl2-(pyridin-4-yl)acetate 95%
5g
$ 593.00

Chemcia Scientific
Pyridin-4-yl-aceticacidtert-butylester ＞98%
1 G
$ 240.00

Apolloscientific
Pyridin-4-yl-aceticacidtert-butylester 95%
1g
$ 435.00

Apolloscientific
Pyridin-4-yl-aceticacidtert-butylester 95%
250mg
$ 175.00

Alichem
tert-Butyl2-(pyridin-4-yl)acetate
1g
$ 171.20

Total 7 raw suppliers

Chemical Property of tert-Butyl 2-(pyridin-4-yl)acetate

Chemical Property:

PSA：39.19000
LogP:1.96580
Storage Temp.:2-8°C
XLogP3:1.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:193.110278721
Heavy Atom Count:14
Complexity:190

Purity/Quality:

95+% ^*data from raw suppliers

tert-Butyl2-(Pyridin-4-yl)acetate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)CC1=CC=NC=C1

Technology Process of tert-Butyl 2-(pyridin-4-yl)acetate

There total 6 articles about tert-Butyl 2-(pyridin-4-yl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 1120-87-2
4-bromopyridin

: 51656-70-3
(2-tert-butoxy-2-oxoethyl)zinc(II) bromide

: 79757-20-3
pyridin-4-ylacetic acid tert-butyl ester

Guidance literature:: With pentaphenylferrocenyl di-tert-butylphosphine; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In tetrahydrofuran; at 70 ℃; for 4h;
DOI:10.1021/ja036792p

Reference yield: 79.0%

: 1120-87-2
4-bromopyridin

: tert-butoxycarbonylmethylzinc bromide tetrahydrofuran salt

: 79757-20-3
pyridin-4-ylacetic acid tert-butyl ester

Guidance literature:: With monophosphine 1,2,3,4,5-pentaphenyl-1'-(di-tert-butylphosphino)ferrocene; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In tetrahydrofuran; at 70 ℃; for 4h; Reagent/catalyst; Inert atmosphere; Sealed tube;
DOI:10.1021/jo401476f

Reference yield: 40.0%

: 107-59-5
tert-Butyl chloroacetate

: potassium (pyridin-4-yl)trifluoroborate

: 79757-20-3
pyridin-4-ylacetic acid tert-butyl ester

Guidance literature:: With chloro(2-dicyclohexylphosphino-2’,4’,6’-triisopropyl-1,1‘-biphenyl)[2-(2’-amino-1,1‘-biphenyl’)]palladium(II); caesium carbonate; In tetrahydrofuran; water; at 100 ℃; for 18h; Inert atmosphere; Sealed tube;
DOI:10.1021/jo400488q