51656-70-3

Basic information

• Product Name: Zinc, bromo[2-(1,1-dimethylethoxy)-2-oxoethyl]-
• Synonyms: Zinc, bromo[2-(1,1-dimethylethoxy)-2-oxoethyl]-;(2-tert-butoxy-2-oxoethyl)zinc(II) bromide;bromo[2-(1,1-dimethylethoxy)-2-oxoethyl]-
• CAS NO: 51656-70-3
• Molecular Formula: C₆H₁₁BrO₂Zn
• Molecular Weight: 260.44434
• EINECS: -0
• Mol File: 51656-70-3.mol
• Article Data: 32

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Zinc, bromo[2-(1,1-dimethylethoxy)-2-oxoethyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Zinc, bromo[2-(1,1-dimethylethoxy)-2-oxoethyl]-(51656-70-3)
• EPA Substance Registry System: Zinc, bromo[2-(1,1-dimethylethoxy)-2-oxoethyl]-(51656-70-3)

Safety Data

• Hazardous Substances Data: 51656-70-3(Hazardous Substances Data)

Usage

General Description

Zinc, bromo[2-(1,1-dimethylethoxy)-2-oxoethyl]- is a complex chemical compound that contains both zinc and bromine atoms. The compound is characterized by the presence of a bromo group attached to a carbon atom that is part of a larger molecular structure containing two dimethylethoxy groups. Zinc, bromo[2-(1,1-dimethylethoxy)-2-oxoethyl]- likely has specific chemical properties and potential applications due to the presence of the zinc and bromine atoms along with the unique structural arrangement of the molecule. Further research and analysis would be necessary to fully understand the potential uses and effects of this chemical compound.

Upstream product

• 5292-43-3 bromoacetic acid tert-butyl ester 
• 7440-66-6 zinc 
• 75-77-4 chloro-trimethyl-silane 

Downstream Products

• 540-88-5 acetic acid tert-butyl ester 
• 926-26-1 di-tert-Butyl succinate 
• 92975-35-4 (E)-4-Methyl-hex-2-enedioic acid 6-tert-butyl ester 1-methyl ester 
• 155495-87-7 tert-butyl 3-(4-toluenesulfonamido)-3-phenylpropanoate 
• 119421-07-7 (3-Chloro-phenylsulfinamoyl)-acetic acid tert-butyl ester 
• 119421-05-5 (4-Methoxy-phenylsulfinamoyl)-acetic acid tert-butyl ester 
• 14734-25-9 succinic acid (methyl)(tert-butyl)diester 
• 150296-35-8 t-butyl (R)-3-hydroxy-3-phenylbutanoate 
• 52178-64-0 (-) S-β-hydroxy β-phenyl n-butanoate de t-butyle 
• 119421-06-6 t-butyl parachlorophenylsulfinamoyl acetate 
• 114153-89-8 (4-Nitro-phenylsulfinamoyl)-acetic acid tert-butyl ester 
• 936699-55-7 tert-butyl (R)-3-(4-chlorophenyl)-3-hydroxypropanoate 
• 390377-26-1 tert-butyl (3R,4S)-4-(N,N-dibenzylamino)-3-hydroxy-6-methylheptanoate 
• 390377-24-9 tert-butyl (3S,4S)-4-(N,N-dibenzylamino)-3-hydroxy-6-methylheptanoate 

Relevant articles and documents

MACROCYCLIC SULFONYLAMIDE DERIVATIVES USEFUL AS NLRP3 INHIBITORS

The present invention relates to macrocyclic compounds, such as macrocyclic sulfonyl amides. The present invention further relates to associated salts, solvates, prodrugs and pharmaceutical compositions, and to the use of such compounds in the treatment and prevention of medical disorders and diseases, most especially by NLRP3 inhibition.

DIFLUOROCYCLOHEXYL DERIVATIVES AS IL-17 MODULATORS

A series of substituted 4,4-difluorocyclohexyl derivatives as defined herein, being potent modulators of human IL-17 activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including inflammatory and autoimmune disorders.

Catalytic Asymmetric Fluorination of Copper Carbene Complexes: Preparative Advances and a Mechanistic Rationale

The Cu-catalyzed reaction of substituted α-diazoesters with fluoride gives α-fluoroesters with ee values of up to 95 %, provided that chiral indane-derived bis(oxazoline) ligands are used that carry bulky benzyl substituents at the bridge and moderately bulky isopropyl groups on their core. The apparently homogeneous solution of CsF in C6F6/hexafluoroisopropanol (HFIP) is the best reaction medium, but CsF in the biphasic mixture CH2Cl2/HFIP also provides good results. DFT studies suggest that fluoride initially attacks the Cu- rather than the C-atom of the transient donor/acceptor carbene intermediate. This unusual step is followed by 1,2-fluoride shift; for this migratory insertion to occur, the carbene must rotate about the Cu?C bond to ensure orbital overlap. The directionality of this rotatory movement within the C2-symmetric binding site determines the sense of induction. This model is in excellent accord with the absolute configuration of the resulting product as determined by X-ray diffraction using single crystals of this a priori wax-like material grown by capillary crystallization.