3-Bromo-7-iodothieno[3,2-C]pyridin-4-amine

Base Information

Chemical Name:3-Bromo-7-iodothieno[3,2-C]pyridin-4-amine
CAS No.:799293-91-7
Molecular Formula:C7H4BrIN2S
Molecular Weight:354.997
Hs Code.:
DSSTox Substance ID:DTXSID001265049
Mol file:799293-91-7.mol

Synonyms:799293-91-7;3-BROMO-7-IODOTHIENO[3,2-C]PYRIDIN-4-AMINE;4-Amino-3-bromo-7-iodothieno[3,2-c]pyridine;3-Bromo-7-iodo-Thieno[3,2-c]pyridin-4-amine;MFCD14706353;SCHEMBL3526550;3-BROMO-7-IODO-THIENO[3,2-C]PYRIDIN-4-YLAMINE;OVNILLPRKSZWCS-UHFFFAOYSA-N;DTXSID001265049;ZGB29391;AKOS025403861;PB26968;AS-51035;DA-23936;SY322492;CS-0051449;3-bromo-7-iodothieno[3,2-c]pyridin-4-ylamine;P11755

Suppliers and Price of 3-Bromo-7-iodothieno[3,2-C]pyridin-4-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
4-Amino-3-bromo-7-iodothieno[3,2-c]pyridine 95+%
1g
$ 1262.00

Matrix Scientific
4-Amino-3-bromo-7-iodothieno[3,2-c]pyridine 95+%
1g
$ 2112.00

Total 9 raw suppliers

Chemical Property of 3-Bromo-7-iodothieno[3,2-C]pyridin-4-amine

Chemical Property:

PSA：67.88000
LogP:3.17570
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:353.83233
Heavy Atom Count:12
Complexity:183

Purity/Quality:

97% ^*data from raw suppliers

4-Amino-3-bromo-7-iodothieno[3,2-c]pyridine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C2=C(C(=CS2)Br)C(=N1)N)I

Technology Process of 3-Bromo-7-iodothieno[3,2-C]pyridin-4-amine

There total 10 articles about 3-Bromo-7-iodothieno[3,2-C]pyridin-4-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 799293-85-9
3-bromo-4-amino-[3,2-c]-thienopyridine

: 799293-91-7
3-bromo-7-iodothieno[3,2-c]pyridin-4-amine

Guidance literature:: With N-iodo-succinimide; In N,N-dimethyl-formamide; at 20 ℃;
DOI:10.1016/j.bmcl.2006.12.035

Reference yield: 50.0%

: 799293-89-3
3-bromo-4-chloro-7-iodo-thieno[3,2-c]pyridine

: 799293-91-7
3-bromo-7-iodothieno[3,2-c]pyridin-4-amine

Guidance literature:: With ammonium hydroxide; In 1,4-dioxane; at 150 ℃;
DOI:10.1016/j.bmcl.2006.09.050

Reference yield:

: 799293-83-7
3-bromothieno[3,2-c]pyridin-4(5H)-one

: 799293-91-7
3-bromo-7-iodothieno[3,2-c]pyridin-4-amine

Guidance literature:: Multi-step reaction with 3 steps

1: 95 percent / POCl₃ / 2.5 h / 135 °C

2: 94 percent / aq. NH₃ / dioxane / 18 h / 150 °C

3: 75 percent / NIS / dimethylformamide / 20 °C

With ammonium hydroxide; N-iodo-succinimide; trichlorophosphate; In 1,4-dioxane; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2006.12.035