2-Amino-1-naphthoic acid

Base Information

• Chemical Name: 2-Amino-1-naphthoic acid
• CAS No.: 79979-69-4
• Molecular Formula: C11H9NO2
• Molecular Weight: 187.19500
• Hs Code.: 2922499990
• DSSTox Substance ID: DTXSID90508722
• Nikkaji Number: J36.385E
• Wikidata: Q82365863
• Mol file: 79979-69-4.mol

Synonyms:2-AMINO-1-NAPHTHOIC ACID;79979-69-4;2-Aminonaphthalene-1-carboxylic acid;2-Amino-1-naphthalenecarboxylic acid;MFCD17012404;2-Amino-1-naphthoicacid;2,3-aminonaphthoic acid;SCHEMBL344096;DTXSID90508722;CXOWHCCVISNMIX-UHFFFAOYSA-N;AKOS005259195;AS-38705;SY128984;CS-0455826;FT-0703291;A917967

Chemical Property of 2-Amino-1-naphthoic acid

Chemical Property:

• Melting Point: 126 °C(Solv: ethanol (64-17-5); water (7732-18-5))
• Boiling Point: 420.7±28.0 °C(Predicted)
• PKA: 5.10±0.10(Predicted)
• PSA: 63.32000
• Density: 1.352±0.06 g/cm3(Predicted)
• LogP: 2.70140
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 187.063328530
• Heavy Atom Count: 14
• Complexity: 229

Purity/Quality:

97% ^*data from raw suppliers

2-amino-1-naphthoicacid 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C=CC(=C2C(=O)O)N

Technology Process of 2-Amino-1-naphthoic acid

There total 8 articles about 2-Amino-1-naphthoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1H-benzo[e]indole-1,2(3H)-dione (5588-87-4) → 2-aminonaphthalene-1-carboxylic acid (79979-69-4)

Guidance literature:

With dihydrogen peroxide;

Reference yield:

1,2,3,4-tetrahydro-2,4-dimethyl-5,6-benzoquinoline (79979-67-2) → 2-aminonaphthalene-1-carboxylic acid (79979-69-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 0.80 g / NaOH / H₂O

2: 1.) KMnO₄; 2.) H₂SO₄ / 1.) acetone, 48 h, RT; 2.) alcohol, 2 h

With sodium hydroxide; potassium permanganate; sulfuric acid; In water;

Reference yield:

1,3-dimethylbenzo[f]quinoline (834-98-0) → 2-aminonaphthalene-1-carboxylic acid (79979-69-4)

Guidance literature:

Multi-step reaction with 3 steps

1: conc. HCl, Sn / 1 h / Heating

2: 0.80 g / NaOH / H₂O

3: 1.) KMnO₄; 2.) H₂SO₄ / 1.) acetone, 48 h, RT; 2.) alcohol, 2 h

With hydrogenchloride; sodium hydroxide; tin; potassium permanganate; sulfuric acid; In water;

upstream raw materials:

1H-benzo[e]indole-1,2(3H)-dione

1,2,3,4-tetrahydro-2,4-dimethyl-N-benzoyl-5,6-benzoquinoline

dihydrogen peroxide

naphthalen-2-ylamine

Downstream raw materials:

4H-benzo[f]quinazoline-1,3-dione

1,3-dichloro benzo[f]quinazoline

3-acetamido-2-naphthoic acid

2-methylbenzo[g]quinazolin-4(3H)-one