Piperazine, 1-(3,4-dimethoxyphenethyl)-4-(o-ethoxyphenyl)-

Base Information

• Chemical Name: Piperazine, 1-(3,4-dimethoxyphenethyl)-4-(o-ethoxyphenyl)-
• CAS No.: 1248-54-0
• Molecular Formula: C22H30 N2 O3
• Molecular Weight: 370.492
• DSSTox Substance ID: DTXSID30154489
• Nikkaji Number: J117.788E
• Wikidata: Q83021745
• Pharos Ligand ID: D8SGCCV6NN88
• ChEMBL ID: CHEMBL3902626
• Mol file: 1248-54-0.mol

Synonyms:Piperazine, 1-(3,4-dimethoxyphenethyl)-4-(o-ethoxyphenyl)-;CHEMBL3902626;1248-54-0;BRN 0629238;1-(3,4-Dimethoxyphenethyl)-4-(o-ethoxyphenyl)piperazine;DTXSID30154489;BDBM50200566

Chemical Property of Piperazine, 1-(3,4-dimethoxyphenethyl)-4-(o-ethoxyphenyl)-

Chemical Property:

• Vapor Pressure: 4.1E-10mmHg at 25°C
• Boiling Point: 499.6°Cat760mmHg
• Flash Point: 139°C
• Density: 1.091g/cm³
• XLogP3: 4.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 8
• Exact Mass: 370.22564282
• Heavy Atom Count: 27
• Complexity: 414

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC1=CC=CC=C1N2CCN(CC2)CCC3=CC(=C(C=C3)OC)OC

Technology Process of Piperazine, 1-(3,4-dimethoxyphenethyl)-4-(o-ethoxyphenyl)-

There total 2 articles about Piperazine, 1-(3,4-dimethoxyphenethyl)-4-(o-ethoxyphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

3,4-dimethoxyphenethyl bromide (40173-90-8) + 1-(2-ethoxyphenyl)piperazine (13339-01-0) → 1-[2-(3,4-dimethoxyphenyl)ethyl]-4-(2-ethoxyphenyl)piperazine (1248-54-0)

Guidance literature:

With triethylamine; In acetonitrile; for 0.0666667h; Microwave irradiation;

DOI:10.1016/j.ejmech.2016.06.052

Reference yield:

→ 1-[2-(3,4-dimethoxyphenyl)ethyl]-4-(2-ethoxyphenyl)piperazine (1248-54-0)

Guidance literature:

1-<2-Ethoxy-phenyl>-piperazin, 3,4-Dimethoxy-phenethylbromid, Xylol, 10h Kochen;

DOI:10.1021/jm00325a021

upstream raw materials:

3,4-dimethoxyphenethyl bromide

1-(2-ethoxyphenyl)piperazine