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Troparil, (+)-

Base Information Edit
  • Chemical Name:Troparil, (+)-
  • CAS No.:74163-84-1
  • Molecular Formula:C16H21NO2
  • Molecular Weight:259.348
  • Hs Code.:
  • UNII:SBH684Y4X1,11M96D7J17
  • DSSTox Substance ID:DTXSID901336295
  • Nikkaji Number:J530.985I
  • Wikipedia:Troparil
  • Mol file:74163-84-1.mol
Troparil, (+)-

Synonyms:(1R-(exo,exo))-8-methyl-3-phenyl-8-azabicyclo(3.2.1)octane-2-carboxylic acid methyl ester;2-methoxycarbonyl-3-phenyltropane;troparil;troparil hydrochloride, (1R-(2-endo,3-exo))-isomer;troparil, (1R-(2-endo,3-exo))-isomer;troparil, (1S-(exo,exo))-isomer;troparil, (2-endo,3-exo)-isomer;troparil, 1,5-naphthalenedisulfonate (1:1), (1R-(exo,exo))-isomer;troparil, 1,5-naphthalenedisulfonate (1:1), (1S-(exo,exo))-isomer;troparil, 1,5-naphthalenedisulfonate (2:1), (1R-(exo,exo))-isomer;troparil, 1,5-naphthalenedisulfonate, (1R-(exo,exo))-isomer;troparil, 1R-(exo,exo)-isomer;Win 35,065;Win 35,065-2;Win 35,065-3;Win 35065;Win 35065-2;Win 35065-3;Win-35,065;Win-35065

Suppliers and Price of Troparil, (+)-
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • American Custom Chemicals Corporation
  • TROPARIL 95.00%
  • 5MG
  • $ 504.66
Total 77 raw suppliers
Chemical Property of Troparil, (+)- Edit
Chemical Property:
  • Vapor Pressure:4.47E-05mmHg at 25°C 
  • Refractive Index:1.54 
  • Boiling Point:350.2°C at 760 mmHg 
  • PKA:9.95±0.60(Predicted) 
  • Flash Point:121.3°C 
  • PSA:29.54000 
  • Density:1.099g/cm3 
  • LogP:2.36380 
  • XLogP3:2.6
  • Hydrogen Bond Donor Count:0
  • Hydrogen Bond Acceptor Count:3
  • Rotatable Bond Count:3
  • Exact Mass:259.157228913
  • Heavy Atom Count:19
  • Complexity:338
Purity/Quality:

99% *data from raw suppliers

TROPARIL 95.00% *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:CN1C2CCC1C(C(C2)C3=CC=CC=C3)C(=O)OC
  • Isomeric SMILES:CN1[C@@H]2CC[C@H]1[C@@H]([C@@H](C2)C3=CC=CC=C3)C(=O)OC
  • Description Troparil is a phenyltropane-based dopamine reuptake inhibitor that is derived from methylecgonidine. It is a stimulant drug used in scientific research. The most commonly used form of troparil is the tartrate salt, but the hydrochloride and naphthalenedisulfonate salts are also available, as well as the free base.
  • Uses Troparil is used in scientific research into the dopamine reuptake transporter. 3H-radiolabelled forms of troparil have been used in humans and animals to map the distribution of dopamine transporters in the brain. It is also used for animal research into stimulant drugs as an alternative to cocaine which produces similar effects, but avoids the stringent licensing requirements for the use of cocaine itself.
Technology Process of Troparil, (+)-

There total 8 articles about Troparil, (+)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
phenylmagnesium bromide; methyl ecgonidine; In diethyl ether; dichloromethane; at -78 - -40 ℃; for 3.5h; Inert atmosphere;
With trifluoroacetic acid; In diethyl ether; dichloromethane; Inert atmosphere;
DOI:10.1016/j.bmc.2013.10.046
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