Methyl 2-[(benzyloxy)(methoxy)amino]-2-methylpropanoate

Base Information

Chemical Name:Methyl 2-[(benzyloxy)(methoxy)amino]-2-methylpropanoate
CAS No.:81308-36-3
Molecular Formula:C13H19NO4
Molecular Weight:253.29400
Hs Code.:
Mol file:81308-36-3.mol

Synonyms:Methyl 2-methyl-2-(methoxy-benzyloxy)amino-propanoate;Methyl 2-[(benzyloxy)(methoxy)amino]-2-methylpropanoate;

Suppliers and Price of Methyl 2-[(benzyloxy)(methoxy)amino]-2-methylpropanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Methyl 2-[(benzyloxy)(methoxy)amino]-2-methylpropanoate

Chemical Property:

PSA：48.00000
LogP:1.93320

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Methyl 2-[(benzyloxy)(methoxy)amino]-2-methylpropanoate

There total 4 articles about Methyl 2-[(benzyloxy)(methoxy)amino]-2-methylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 67-56-1
methanol

: 135765-53-6
C₁₂H₁₆ClNO₃

: 81308-36-3
C₁₃H₁₉NO₄

Guidance literature:: With triethylamine; 1.) -20 deg C, 6 h, 2.) 20 deg C, 1 h;
DOI:10.1007/BF00961356

Reference yield: 39.5%

: 76170-90-6
methyl ester of α-(N-chloro-N-methoxyamino)isobutyric acid

: 100-51-6,185532-71-2
benzyl alcohol

: 81308-36-3
C₁₃H₁₉NO₄

Guidance literature:: With triethylamine; 1.) -78 deg C, 1h, 2.) 20 deg C, 1h;
DOI:10.1016/0040-4020(81)85018-1

Reference yield:

: 23426-63-3
2-bromo-2-methylpropionic acid methyl ester

: 81308-36-3
C₁₃H₁₉NO₄

Guidance literature:: Multi-step reaction with 3 steps

1: 35.3 percent / 75 h / 60 - 70 °C

2: t-BuOCl / diethyl ether / 1 h / -78 °C

3: 39.5 percent / Et₃N / 1.) -78 deg C, 1h, 2.) 20 deg C, 1h

With tert-butylhypochlorite; triethylamine; In diethyl ether;
DOI:10.1016/0040-4020(81)85018-1