N-[(5-amino-1,3,4-thiadiazol-2-yl)methyl]benzamide

Base Information

Chemical Name:N-[(5-amino-1,3,4-thiadiazol-2-yl)methyl]benzamide
CAS No.:81837-98-1
Molecular Formula:C10H10N4OS
Molecular Weight:234.282
Hs Code.:
DSSTox Substance ID:DTXSID80510132
Wikidata:Q82368221
Mol file:81837-98-1.mol

Synonyms:N-[(5-amino-1,3,4-thiadiazol-2-yl)methyl]benzamide;81837-98-1;N-((5-Amino-1,3,4-thiadiazol-2-yl)methyl)benzamide;SCHEMBL26132832;DTXSID80510132;MFCD13248746;AKOS005173926;LS-04038;CS-0317151

Suppliers and Price of N-[(5-amino-1,3,4-thiadiazol-2-yl)methyl]benzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
N-[(5-Amino-1,3,4-thiadiazol-2-yl)methyl]benzamide
500mg
$ 219.00

Crysdot
N-((5-Amino-1,3,4-thiadiazol-2-yl)methyl)benzamide 97%
5g
$ 752.00

Total 6 raw suppliers

Chemical Property of N-[(5-amino-1,3,4-thiadiazol-2-yl)methyl]benzamide

Chemical Property:

PSA：113.36000
LogP:1.55520
XLogP3:0.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:234.05753213
Heavy Atom Count:16
Complexity:245

Purity/Quality:

98%min ^*data from raw suppliers

N-[(5-Amino-1,3,4-thiadiazol-2-yl)methyl]benzamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(=O)NCC2=NN=C(S2)N

Technology Process of N-[(5-amino-1,3,4-thiadiazol-2-yl)methyl]benzamide

There total 4 articles about N-[(5-amino-1,3,4-thiadiazol-2-yl)methyl]benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 495-69-2,140480-84-8,21251-67-2,91787-63-2,66407-11-2
Hippuric Acid

: 79-19-6
thiosemicarbazide

: 81837-98-1
N-((5-amino-1,3,4-thiadiazol-2-yl)methyl)benzamide

Guidance literature:: With trichlorophosphate; for 1h; Reflux;
DOI:10.3390/molecules22060995

Reference yield: 70.0%

: 83530-35-2
1-hippuroyl thiosemicarbazide

: 81837-98-1
N-((5-amino-1,3,4-thiadiazol-2-yl)methyl)benzamide

Guidance literature:: With sulfuric acid;

Reference yield:

: 98-88-4
benzoyl chloride

: 81837-98-1
N-((5-amino-1,3,4-thiadiazol-2-yl)methyl)benzamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydroxide / water

1.2: Cooling

2.1: trichlorophosphate / 1 h / Reflux

With sodium hydroxide; trichlorophosphate; In water;
DOI:10.3390/molecules22060995