Phenyl(2-phenyl-1,3-benzoxazol-5-yl)methanone

Base Information

• Chemical Name: Phenyl(2-phenyl-1,3-benzoxazol-5-yl)methanone
• CAS No.: 82593-17-7
• Molecular Formula: C20H13NO2
• Molecular Weight: 299.329
• DSSTox Substance ID: DTXSID80513380
• Nikkaji Number: J861.746E
• Wikidata: Q82373167
• Mol file: 82593-17-7.mol

Synonyms:82593-17-7;SCHEMBL19945200;DTXSID80513380;Phenyl(2-phenyl-1,3-benzoxazol-5-yl)methanone

Chemical Property of Phenyl(2-phenyl-1,3-benzoxazol-5-yl)methanone

Chemical Property:

• XLogP3: 4.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 299.094628657
• Heavy Atom Count: 23
• Complexity: 412

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=NC3=C(O2)C=CC(=C3)C(=O)C4=CC=CC=C4

Technology Process of Phenyl(2-phenyl-1,3-benzoxazol-5-yl)methanone

There total 11 articles about Phenyl(2-phenyl-1,3-benzoxazol-5-yl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

3-benzoylamino-4-hydroxybenzophenone (82593-18-8) → (2-phenyl-5-benzoxazolyl)phenylmethanone (82593-17-7)

Guidance literature:

at 200 ℃; for 2h; horizontal test tube, under vacuum;

Reference yield: 55.0%

Benzotrichlorid (98-07-7) + 2-amino-phenol (95-55-6) → 2-phenylbenzo[d]oxazole (833-50-1) + (2-phenyl-5-benzoxazolyl)phenylmethanone (82593-17-7)

Guidance literature:

With PPA; at 100 - 120 ℃; for 10h;

DOI:10.1080/00397919809458691

Reference yield: 50.0%

2-phenylbenzo[d]oxazole (833-50-1) + benzoyl chloride (98-88-4) → (2-phenyl-5-benzoxazolyl)phenylmethanone (82593-17-7)

Guidance literature:

With zinc(II) oxide; at 200 - 210 ℃; for 10h;

upstream raw materials:

2-phenylbenzo[d]oxazole

benzoyl chloride

2-(benzamido)phenyl benzoate

3-benzoylamino-4-hydroxybenzophenone