(4-AMINO-6-HYDROXY-PYRIMIDIN-2-YLSULFANYL)-ACETIC ACID

Base Information

• Chemical Name: (4-AMINO-6-HYDROXY-PYRIMIDIN-2-YLSULFANYL)-ACETIC ACID
• CAS No.: 66902-63-4
• Molecular Formula: C6H7N3O3S
• Molecular Weight: 201.2031
• Hs Code.: 2933599090
• Mol file: 66902-63-4.mol

Synonyms:4-Amino-6-oxypyrimidine-2-thioglycollic acid;Pyrimidine-2-thioglycollic acid,4-amino-6-hydroxy;USAF EL-10;

Chemical Property of (4-AMINO-6-HYDROXY-PYRIMIDIN-2-YLSULFANYL)-ACETIC ACID

Chemical Property:

• Vapor Pressure: 3.09E-08mmHg at 25°C
• Boiling Point: 420.1°Cat760mmHg
• Flash Point: 207.9°C
• PSA: 134.63000
• Density: 1.77g/cm³
• LogP: 0.52230

Purity/Quality:

97% ^*data from raw suppliers

2-[(4-amino-6-oxo-1,6-dihydropyrimidin-2-yl)sulfanyl]aceticAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (4-AMINO-6-HYDROXY-PYRIMIDIN-2-YLSULFANYL)-ACETIC ACID

There total 3 articles about (4-AMINO-6-HYDROXY-PYRIMIDIN-2-YLSULFANYL)-ACETIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2,3-dihydro-5H-7-amino-thiazolo[3,2-a]pyrimdine-3,5-dione → (4-amino-6-oxo-1,6-dihydro-pyrimidin-2-ylmercapto)-acetic acid (66902-63-4)

Guidance literature:

With water; for 3h; Reflux;

Reference yield: 70.0%

6-Amino-2-thiouracil (1004-40-6) + sodium monochloroacetic acid (3926-62-3) → (4-amino-6-oxo-1,6-dihydro-pyrimidin-2-ylmercapto)-acetic acid (66902-63-4)

Guidance literature:

With sodium hydroxide; for 3h; Ambient temperature;

Reference yield:

6-Amino-2-thiouracil (1004-40-6) + chloroacetic acid (79-11-8) → (4-amino-6-oxo-1,6-dihydro-pyrimidin-2-ylmercapto)-acetic acid (66902-63-4)

Guidance literature:

upstream raw materials:

6-Amino-2-thiouracil

chloroacetic acid

sodium monochloroacetic acid