Carbamic acid, [2-[(4-aminophenyl)amino]-2-oxoethyl]-, 1,1-dimethylethyl ester

Base Information

Chemical Name:Carbamic acid, [2-[(4-aminophenyl)amino]-2-oxoethyl]-, 1,1-dimethylethyl ester
CAS No.:83209-85-2
Molecular Formula:C13H19N3O3
Molecular Weight:265.30800
Hs Code.:

Synonyms:[(4-Amino-phenylcarbamoyl)-methyl]-carbamic acid tert-butyl ester;N-(4-aminophenyl)-α-[(tert-butoxycarbonyl)amino]acetamide;

Suppliers and Price of Carbamic acid, [2-[(4-aminophenyl)amino]-2-oxoethyl]-, 1,1-dimethylethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Carbamic acid, [2-[(4-aminophenyl)amino]-2-oxoethyl]-, 1,1-dimethylethyl ester

Chemical Property:

PSA：93.45000
LogP:2.77710

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses tert-Butyl (2-((4-Aminophenyl)amino)-2-oxoethyl)carbamate is an intermediate in the synthesis of (E)-2-Formamido-N-(4-((4-(4-hydroxybutyl)phenyl)diazenyl)phenyl)acetamide (F792100), a compound useful in organic synthesis.

Technology Process of Carbamic acid, [2-[(4-aminophenyl)amino]-2-oxoethyl]-, 1,1-dimethylethyl ester

There total 3 articles about Carbamic acid, [2-[(4-aminophenyl)amino]-2-oxoethyl]-, 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 4530-20-5
BOC-glycine

: 106-50-3
1,4-phenylenediamine

: 83209-85-2
N-(4-aminophenyl)-α-<(tert-butoxycarbonyl)amino>acetamide

Guidance literature:: With dicyclohexyl-carbodiimide; In tetrahydrofuran; at 25 ℃; for 24h;
DOI:10.1021/jo00376a057

Reference yield: 38.0%

: 82518-64-7
N-(4-nitrophenyl)-α-<(tert-butoxycarbonyl)amino>acetamide

: 83209-85-2
N-(4-aminophenyl)-α-<(tert-butoxycarbonyl)amino>acetamide

Guidance literature:: With iron; acetic acid; In water; acetone; for 5h; Heating;
DOI:10.1021/jo00376a057

Reference yield:

: 100-01-6,104810-17-5
4-nitro-aniline

: 83209-85-2
N-(4-aminophenyl)-α-<(tert-butoxycarbonyl)amino>acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: 33 percent / 1,3-dicyclohexylcarbodiimide / tetrahydrofuran / 18 h / 25 °C

2: 38 percent / iron, glacial acetic acid / acetone; H₂O / 5 h / Heating

With iron; acetic acid; dicyclohexyl-carbodiimide; In tetrahydrofuran; water; acetone;
DOI:10.1021/jo00376a057