2-Methoxy-5-methyl-3-nitroaniline

Base Information

Chemical Name:2-Methoxy-5-methyl-3-nitroaniline
CAS No.:83604-27-7
Molecular Formula:C8H10N2O3
Molecular Weight:182.179
Hs Code.:
DSSTox Substance ID:DTXSID10529297
Wikidata:Q82399644

Synonyms:2-Methoxy-5-methyl-3-nitroaniline;83604-27-7;Benzenamine, 2-methoxy-5-methyl-3-nitro-;SCHEMBL10426800;DTXSID10529297

Suppliers and Price of 2-Methoxy-5-methyl-3-nitroaniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 2-Methoxy-5-methyl-3-nitroaniline

Chemical Property:

XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:182.06914219
Heavy Atom Count:13
Complexity:192

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C(=C1)[N+](=O)[O-])OC)N

Technology Process of 2-Methoxy-5-methyl-3-nitroaniline

There total 1 articles about 2-Methoxy-5-methyl-3-nitroaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 29455-11-6
2,6-dinitro-4-methylanisole

: 83604-27-7
2-methoxy-3-nitro-5-methylaniline

Guidance literature:: With ammonium sulfide; In methanol; for 0.666667h; Heating;
DOI:10.1021/ja00329a059

Reference yield: 90.0%

: 75-44-5
phosgene

: 83604-27-7
2-methoxy-3-nitro-5-methylaniline

: 83604-28-8
1,3-bis(2-methoxy-3-nitro-5-methylphenyl)urea

Guidance literature:: With pyridine; In tetrahydrofuran; for 30h; Heating;
DOI:10.1021/ja00329a059

Reference yield:

: 83604-27-7
2-methoxy-3-nitro-5-methylaniline

: 83604-32-4
1,3-bis<2-methoxy-3-(1-tetrahydro-(3H)-pyrimidinonyl)-5-methylphenyl>tetrahydro-2(1H)-pyrimidinone

Guidance literature:: Multi-step reaction with 5 steps

1: 90 percent / pyridine / tetrahydrofuran / 30 h / Heating

2: 70 percent / NaOH, benzyltriethylammonium bromide / benzene; H₂O / 96 h / 46 °C

3: 97.6 percent / iron powder, hydrochloric acid / ethanol; H₂O / 3 h / Heating

4: CH₂Cl₂ / 48.5 h / slight initial warming

5: 61.8 percent / potassium tert-butoxide / 2-methyl-propan-2-ol / 15 h / 32 °C

With pyridine; hydrogenchloride; sodium hydroxide; potassium tert-butylate; benzyltriethylammonium bromide; iron; In tetrahydrofuran; ethanol; dichloromethane; water; tert-butyl alcohol; benzene;
DOI:10.1021/ja00329a059