4-(2-Chlorophenyl)-2-azetidinone

Base Information

Chemical Name:4-(2-Chlorophenyl)-2-azetidinone
CAS No.:83716-63-6
Molecular Formula:C9H8ClNO
Molecular Weight:181.622
Hs Code.:
European Community (EC) Number:829-389-2

Synonyms:4-(2-Chlorophenyl)-2-azetidinone;4-(2-chlorophenyl)azetidin-2-one;83716-63-6;4-(o-chlorophenyl)-2-azetidinone;AKOS006292290;EN300-200360;Z1198168153

Suppliers and Price of 4-(2-Chlorophenyl)-2-azetidinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(2-Chlorophenyl)-2-azetidinone
100mg
$ 240.00

AK Scientific
4-(2-Chlorophenyl)-2-azetidinone
100mg
$ 262.00

AK Scientific
4-(2-Chlorophenyl)-2-azetidinone
2.5g
$ 1232.00

Acrotein
4-(2-Chlorophenyl)-2-azetidinone 97%
1g
$ 458.33

Total 7 raw suppliers

Chemical Property of 4-(2-Chlorophenyl)-2-azetidinone

Chemical Property:

PSA：29.10000
LogP:2.22980
XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:181.0294416
Heavy Atom Count:12
Complexity:195

Purity/Quality:

97% ^*data from raw suppliers

4-(2-Chlorophenyl)-2-azetidinone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(NC1=O)C2=CC=CC=C2Cl

Technology Process of 4-(2-Chlorophenyl)-2-azetidinone

There total 5 articles about 4-(2-Chlorophenyl)-2-azetidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 1189-71-5
isocyanate de chlorosulfonyle

: 2039-87-4,107830-52-4,26125-41-7
2-chlorostyrene

: 83716-63-6
(+/-)-4-(2-chlorophenyl)-2-azetidinone

Guidance literature:: isocyanate de chlorosulfonyle; 2-chlorostyrene; In toluene; at 20 ℃; for 8h;

With sodium carbonate; sodium sulfite; In water; toluene;
DOI:10.1002/adsc.200505434

Reference yield: 35.0%

: 566198-10-5
(+/-)-trimethylsilyl β-(N-trimethylsilylamino)-β-(2-chlorophenyl)propionate

: 83716-63-6
(+/-)-4-(2-chlorophenyl)-2-azetidinone

Guidance literature:: With ethylmagnesium bromide; In diethyl ether; at 0 - 20 ℃; for 14h;
DOI:10.1007/s00706-002-0485-8

Reference yield:

: 68208-20-8,740794-79-0
3-amino-3-(2-chloro-phenyl)-propionic acid

: 83716-63-6
(+/-)-4-(2-chlorophenyl)-2-azetidinone

Guidance literature:: Multi-step reaction with 2 steps

1.1: benzene / 0.25 h / Heating

1.2: 87 percent / Et₃N / benzene / 2 h / Heating

2.1: 35 percent / EtMgBr / diethyl ether / 14 h / 0 - 20 °C

With ethylmagnesium bromide; In diethyl ether; benzene;
DOI:10.1007/s00706-002-0485-8