(7-BroMo-4-chloro-1-ethyl...

Base Information

• Chemical Name: (7-BroMo-4-chloro-1-ethyl...
• CAS No.: 842144-05-2
• Molecular Formula: C10H8BrClN4
• Molecular Weight: 299.557
• Hs Code.: 2933990090
• Mol file: 842144-05-2.mol

Synonyms:C-8906;(7-bromo-4-chloro-1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)acetonitrile;2-(7-Bromo-4-chloro-1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)acetonitrile;(7-bromo-7-chloro-1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)acetonitrile;

Chemical Property of (7-BroMo-4-chloro-1-ethyl...

Chemical Property:

• PSA: 54.50000
• LogP: 2.93318

Purity/Quality:

97% ^*data from raw suppliers

2-{7-Bromo-4-chloro-1-ethylimidazo[4,5-c]pyridin-2-yl}acetonitrile ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (7-BroMo-4-chloro-1-ethyl...

There total 4 articles about (7-BroMo-4-chloro-1-ethyl... which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-[5-romo-2-chloro-4-(ethylamino)-3-pyridinyl]-2-cyanoacetamide (842144-04-1) → (7-bromo-4-chloro-1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)acetonitrile (842144-05-2)

Guidance literature:

With acetic acid; at 100 ℃; for 3h;

Reference yield:

ethyl-(3-bromo-5-nitropyridin-4-yl)amine (607371-01-7) → (7-bromo-4-chloro-1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)acetonitrile (842144-05-2)

Guidance literature:

Multi-step reaction with 3 steps

1: hydrogenchloride; water

2: 1,2-dichloro-ethane; 4-methyl-morpholine / dichloromethane; ethyl acetate; water

3: acetic acid

With 4-methyl-morpholine; 1,2-dichloro-ethane; In hydrogenchloride; dichloromethane; water; acetic acid; ethyl acetate;

Reference yield:

5-bromo-2-chloro-N4-ethylpyridine-3,4-diamine (842144-03-0) → (7-bromo-4-chloro-1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)acetonitrile (842144-05-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 1,2-dichloro-ethane; 4-methyl-morpholine / dichloromethane; ethyl acetate; water

2: acetic acid

With 4-methyl-morpholine; 1,2-dichloro-ethane; In dichloromethane; water; acetic acid; ethyl acetate;

upstream raw materials:

N-[5-romo-2-chloro-4-(ethylamino)-3-pyridinyl]-2-cyanoacetamide

ethyl-(3-bromo-5-nitropyridin-4-yl)amine

5-bromo-2-chloro-N₄-ethylpyridine-3,4-diamine

3-bromo-4-chloro-5-nitropyridine

Downstream raw materials:

(7-bromo-4-chloro-1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)hydroxyiminoacetonitrile

2-(4-amino-1,2,5-oxadiazol-3-yl)-4-chloro-1-ethyl-1H-imidazo[4,5-c]pyridin-7-ol

4-(7-bromo-4-chloro-1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-ylamine

1,1-dimethylethyl (3S)-3-({[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-4-(3-hydroxy-3-methyl-1-butyn-1-yl)-1H-imidazo[4,5-c]pyridin-7-yl]oxy}methyl)-1-piperidinecarboxylate