Phosphonic acid, dipropyl ester

Base Information

• Chemical Name: Phosphonic acid, dipropyl ester
• CAS No.: 1809-21-8
• Molecular Formula: C6H15 O3 P
• Molecular Weight: 166.157
• Hs Code.: 2920901900
• NSC Number: 79865
• UNII: P4R35UZG89
• DSSTox Substance ID: DTXSID7075135
• Wikidata: Q82003166
• Mol file: 1809-21-8.mol

Synonyms:Phosphonic acid, dipropyl ester;DIPROPYL PHOSPHONATE;P4R35UZG89;NSC-79865;EINECS 217-318-2;di-n-propyl phosphite;UNII-P4R35UZG89;SCHEMBL282709;DIPROPOXYPHOSPHINE OXIDE;DTXSID7075135;Propyl phosphonate, (PrO)2HPO;NSC79865;NSC 79865;PHOSPHOROUS ACID, DIPROPYL ESTER;PROPYL PHOSPHONATE ((PRO)2HPO);PROPYL ALCOHOL, HYDROGEN PHOSPHITE

Chemical Property of Phosphonic acid, dipropyl ester

Chemical Property:

• Vapor Pressure: 0.405mmHg at 25°C
• Refractive Index: n20/D 1.417(lit.)
• Boiling Point: 203 °C at 760 mmHg
• Flash Point: 96.1 °C
• PSA: 59.00000
• Density: g/cm³
• LogP: 2.22930
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 6
• Exact Mass: 165.06805630
• Heavy Atom Count: 10
• Complexity: 85

Purity/Quality:

99% ^*data from raw suppliers

DIPROPYL PHOSPHITE 95.00% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-27-28-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCO[P+](=O)OCCC

Technology Process of Phosphonic acid, dipropyl ester

There total 19 articles about Phosphonic acid, dipropyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

propan-1-ol (71-23-8) → di-n-propyl phosphonate (1809-21-8)

Guidance literature:

With pyridine; phosphorus trichloride; In diethyl ether; at 0 - 20 ℃;

DOI:10.1021/jo200522w

Reference yield: 95.5%

propan-1-ol (71-23-8) + Dimethyl phosphite (868-85-9) → di-n-propyl phosphonate (1809-21-8)

Guidance literature:

With sodium hydroxide; at 140 ℃; under 760.051 Torr; Reflux; Inert atmosphere;

Reference yield: 93.0%

propan-1-ol (71-23-8) → 1-Chloropropane (540-54-5) + di-n-propyl phosphonate (1809-21-8)

Guidance literature:

With phosphorus trichloride; at 0 - 50 ℃; for 50h;

DOI:10.1080/10426500903444366

upstream raw materials:

propan-1-ol

tri-n-propyl phosphite

sodium n-propoxide

phosphonic acid diethyl ester

Downstream raw materials:

(α-hydroxy-3-nitro-benzyl)-phosphonic acid dipropyl ester

(α-hydroxy-benzyl)-phosphonic acid dipropyl ester

propyl propionate

Octyl-phosphonsaeure-dipropylester

Refernces

• 1、 -. "Method for preparing phosphite diester by transesterification". Paragraph 0026. . Retrieved 2020/01/25.
• 2、 Bálint, Erika,Tajti, ádám,Tóth, Nóra,Keglevich, Gy rgy. "Continuous flow alcoholysis of dialkyl h-phosphonates with aliphatic alcohols". . . Retrieved 2018/07/13.