2-(4-Hydroxyphenyl)-7-methoxy-6-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one

Base Information

Chemical Name:2-(4-Hydroxyphenyl)-7-methoxy-6-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one
CAS No.:19879-30-2
Molecular Formula:C₂₁H₂₂O₄
Molecular Weight:338.403
Hs Code.:
DSSTox Substance ID:DTXSID90941731
Wikidata:Q72444917
Metabolomics Workbench ID:27205
ChEMBL ID:CHEMBL4783450
Mol file:19879-30-2.mol

Synonyms:(2S)-2,3-dihydro-2-(4-hydroxyphenyl)-7-methoxy-6-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one;4'-hydroxy-7-methoxy-6-(3-methyl-2-butenyl)flavanone;7-O-methylbavachin;bavachinin;bavachinin A

Suppliers and Price of 2-(4-Hydroxyphenyl)-7-methoxy-6-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Bavachinin A
20mg
$ 552.00

TRC
Bavachinin
1mg
$ 45.00

Sigma-Aldrich
Bavachinin ≥95% (LC/MS-ELSD)
1mg
$ 247.00

Medical Isotopes, Inc.
Bavachinin 98%
1000 mg
$ 1067.00

DC Chemicals
BavachininA >98%,StandardReferencesGrade
20 mg
$ 280.00

CSNpharm
Bavachinin
5mg
$ 65.00

Crysdot
Bavachinin 98+%
10mg
$ 102.00

ChemScene
Bavachinin 99.96%
5mg
$ 72.00

ChemScene
Bavachinin 99.96%
10mg
$ 96.00

Cayman Chemical
Bavachinin ≥98%
5mg
$ 94.00

Total 68 raw suppliers

Chemical Property of 2-(4-Hydroxyphenyl)-7-methoxy-6-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one

Chemical Property:

Vapor Pressure:3.76E-12mmHg at 25°C
Melting Point:139-145 °C
Refractive Index:1.589
Boiling Point:537.1 °C at 760 mmHg
PKA:9.66±0.30(Predicted)
Flash Point:190.3 °C
PSA：55.76000
Density:1.182 g/cm³
LogP:4.61600
Storage Temp.:?20°C
XLogP3:4.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:338.15180918
Heavy Atom Count:25
Complexity:488

Purity/Quality:

≥98% ^*data from raw suppliers

Bavachinin A ^*data from reagent suppliers

Safty Information:

Pictogram(s): N
Hazard Codes:N
Statements: 50
Safety Statements: 61

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=CCC1=CC2=C(C=C1OC)OC(CC2=O)C3=CC=C(C=C3)O)C
Uses Bavachinin is a natural component of Psoralea corylifolia which has been shown to improve insulin-dependant glucose uptake through insuling signaling AMPK activation. Also used as peroxisome proliferator activated receptor γ agonists in the treatment of diabetes.

Technology Process of 2-(4-Hydroxyphenyl)-7-methoxy-6-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one

There total 23 articles about 2-(4-Hydroxyphenyl)-7-methoxy-6-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 128961-19-3
7-methoxy-2-(4-(methoxymethoxy)phenyl)-6-(3-methylbut-2-en-1-yl)chroman-4-one

: 129097-15-0,19879-30-2
2-(4-hydroxyphenyl)-7-methoxy-6-(3-methylbut-2-en-1-yl)chroman-4-one

Guidance literature:: With hydrogenchloride; In methanol; water; for 0.5h; Reflux;

Reference yield:

: 28448-83-1
2′-hydroxyl-4′-methoxyl-5′-isopentenylacetophenone

: 129097-15-0,19879-30-2
2-(4-hydroxyphenyl)-7-methoxy-6-(3-methylbut-2-en-1-yl)chroman-4-one

Guidance literature:: Multi-step reaction with 3 steps

1: 51 percent / potassium trimethylsilanolate / ethanol / 3 h / Heating

2: 69 percent / KF - Celite / methanol / 48 h / Heating

3: 89 percent / concd HCl / methanol / 30 h / Heating

With hydrogenchloride; potassium fluoride; KF - Celite; potassium trimethylsilonate; In methanol; ethanol;

Reference yield:

: 128961-25-1
1-(4-methoxy-2-((3-methylbut-2-en-1-yl)oxy)phenyl)ethan-1-one

: 129097-15-0,19879-30-2
2-(4-hydroxyphenyl)-7-methoxy-6-(3-methylbut-2-en-1-yl)chroman-4-one

Guidance literature:: Multi-step reaction with 4 steps

1: 86 percent / PhNEt₂ / 4 h / Heating

2: 51 percent / potassium trimethylsilanolate / ethanol / 3 h / Heating

3: 69 percent / KF - Celite / methanol / 48 h / Heating

4: 89 percent / concd HCl / methanol / 30 h / Heating

With hydrogenchloride; potassium fluoride; KF - Celite; potassium trimethylsilonate; N,N-diethylaniline; In methanol; ethanol;