2,4,5-Triphenylthiazole

Base Information

• Chemical Name: 2,4,5-Triphenylthiazole
• CAS No.: 2104-11-2
• Molecular Formula: C21H15NS
• Molecular Weight: 313.423
• European Community (EC) Number: 632-562-3
• DSSTox Substance ID: DTXSID50175252
• Nikkaji Number: J1.748.129K
• Wikidata: Q83045542
• Mol file: 2104-11-2.mol

Synonyms:2,4,5-Triphenylthiazole;2,4,5-triphenyl-1,3-thiazole;2104-11-2;Triphenylthiazole;Thiazole, triphenyl-;SCHEMBL9768642;DTXSID50175252;AKOS002918735;2-(4,5-diphenyl-2-thiazolyl)-benzene;AB-131/40897078

Chemical Property of 2,4,5-Triphenylthiazole

Chemical Property:

• Vapor Pressure: 1.43E-08mmHg at 25°C
• Boiling Point: 470.4°Cat760mmHg
• Flash Point: 234.5°C
• PSA: 41.13000
• Density: 1.169g/cm³
• LogP: 6.14410
• XLogP3: 5.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 313.09252066
• Heavy Atom Count: 23
• Complexity: 353

Purity/Quality:

99% ^*data from raw suppliers

2,4,5-TRIPHENYLTHIAZOLE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=C(SC(=N2)C3=CC=CC=C3)C4=CC=CC=C4

Technology Process of 2,4,5-Triphenylthiazole

There total 30 articles about 2,4,5-Triphenylthiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

iodobenzene (591-50-4) + 4,5-diphenylthiazole (1826-15-9) → 2,4,5-triphenylthiazole (2104-11-2)

Guidance literature:

With [Pd(1,10-phenanthroline)₂](PF₆)₂; caesium carbonate; In N,N-dimethyl acetamide; at 140 ℃; for 40h; regioselective reaction;

DOI:10.1039/c3sc52199k

Reference yield: 94.0%

4-bromo-2,5-diphenylthiazole (130161-15-8) + phenylboronic acid (98-80-6) → 2,4,5-triphenylthiazole (2104-11-2)

Guidance literature:

With potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In toluene; at 80 ℃; for 2h;

DOI:10.1021/ol025688u

Reference yield: 90.0%

iodobenzene (591-50-4) + 2,4-diphenylthiazole (1826-14-8) → 2,4,5-triphenylthiazole (2104-11-2)

Guidance literature:

With dichloro(2,2'-bipyridine)palladium(II); silver carbonate; In 1,4-dioxane; at 120 ℃; for 12h; regioselective reaction;

DOI:10.1039/c3sc52199k

upstream raw materials:

benzenecarbothioamide

desyl bromide

α-benzamidylbenzyl phenyl ketone

benzamide

Downstream raw materials:

2,4,5-triphenyloxazole