1826-15-9

Basic information

• Product Name: Thiazole, 4,5-diphenyl-
• CAS NO: 1826-15-9
• Molecular Formula: C15H11NS
• Molecular Weight: 237.325
• Mol File: 1826-15-9.mol

Chemical Properties

• CAS DataBase Reference: Thiazole, 4,5-diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Thiazole, 4,5-diphenyl-(1826-15-9)
• EPA Substance Registry System: Thiazole, 4,5-diphenyl-(1826-15-9)

Safety Data

• Hazardous Substances Data: 1826-15-9(Hazardous Substances Data)

Upstream product

• 3704-40-3 2,5-diphenyl-1,3-thiazole 
• 97195-28-3 N-(2-oxo-1,2-diphenylethyl)formamide 
• 98-80-6 phenylboronic acid 
• 1826-12-6 4-phenyl-thiazole 
• 591-50-4 iodobenzene 
• 2168-78-7 methyl dithiobenzoate 
• 88333-03-3 Benzyl isocyanide 
• 885-75-6 2-amino-1,2-diphenyl-ethanone; hydrochloride 
• 119-53-9 2-hydroxy-2-phenylacetophenone 
• 3469-17-8 2-diazo-1,2-diphenylethan-1-one 
• 7647-01-0 hydrogenchloride 
• 73753-33-0 2-hydrazino-4,5-diphenyl-thiazole 
• 7722-84-1 dihydrogen peroxide 
• 77287-34-4 formamide 

Downstream Products

• 2104-11-2 2,4,5-triphenylthiazole 
• 120332-29-8 (diphenylthiazolyl)toluene 
• 70031-89-9 4-(4,5-diphenyl-thiazol-2-yl)-pyridine 

Relevant articles and documents

Programmed synthesis of arylthiazoles through sequential C-H couplings

A programmed synthesis of privileged arylthiazoles via sequential C-H couplings catalyzed by palladium or nickel catalysts has been accomplished. This versatile protocol can supply all possible arylthiazole substitution patterns (2-aryl, 4-aryl, 5-aryl, 2

An easy access to 4,5-disubstituted thiazoles via base-induced click reaction of active methylene isocyanides with methyl dithiocarboxylates

An efficient synthesis of 4,5-disubstituted thiazoles via base-induced cyclization of active methylene isocyanides such as tosylmethyl isocyanide, ethyl isocyanoacetate, and arylmethyl isocyanides with methyl arene- and hetarenecarbodithioates is reported

N-H Insertion reactions of rhodium carbenoids. Part 5: A convenient route to 1,3-azoles

Dirhodium(II) carboxylate catalysed reaction of diazocarbonyl compounds 2 in the presence of primary amides 1 results in the formation of α-acylaminoketones 3 (12 examples) by N-H insertion reaction of the intermediate rhodium carbene. The 1,4-dicarbonyl

Mechanism of Base-catalysed Hydrogen-Deuterium Exchange in Thiazolium Ion: Evidence for the Involvement of a Tetrahedral Intermediate

The mechanism of base-catalysed hydrogen-deuterium exchange of 2-H in the thiazolium ion has been examined by 1H n.m.r. spectroscopy, using small and sterically hindered nucleophiles.Rapid H-D exchange is observed in Me2SO in the cases of 3,4,5-trimethyl- (1), 3-methyl-4,5-diphenyl- (2), 3,5-dimethyl-4-phenyl- (3), and 3,4-dimethyl-5-phenyl-thiazolium iodide (4), when small nucleophiles (KOD-D2O or KOCD3-DOCD3; 0.016M; 25 deg C) are employed.Utilization of a hindered nucleophile however results in a slow exhange of 2-H in (1), (3), and (4), concomitant with H-D exchange of the 4- and 5-methyl exchange of 2-H is detected in the case of (2) with the hindered nucleophile.These observations are ascribed to the formation of a tetrahedral intermediate as a prerequisite of the exchange reaction.