2-(3-Fluorophenyl)-5-phenyl-1,3,4-oxadiazole

Base Information

Chemical Name:2-(3-Fluorophenyl)-5-phenyl-1,3,4-oxadiazole
CAS No.:62681-97-4
Molecular Formula:C₁₄H₉FN₂O
Molecular Weight:240.237
Hs Code.:
European Community (EC) Number:263-693-0
NSC Number:90363
DSSTox Substance ID:DTXSID10211741
Nikkaji Number:J307.116B
Wikidata:Q83086721

Synonyms:2-(3-Fluorophenyl)-5-phenyl-1,3,4-oxadiazole;62681-97-4;EINECS 263-693-0;NSC90363;DTXSID10211741;NSC 90363;NSC-90363;BB 0238439;2-(3-Fluoro-phenyl)-5-phenyl-[1,3,4]oxadiazol e

Suppliers and Price of 2-(3-Fluorophenyl)-5-phenyl-1,3,4-oxadiazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 8 raw suppliers

Chemical Property of 2-(3-Fluorophenyl)-5-phenyl-1,3,4-oxadiazole

Chemical Property:

Vapor Pressure:9.8E-06mmHg at 25°C
Boiling Point:383.3°Cat760mmHg
Flash Point:185.6°C
Density:1.241g/cm³
XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:240.06989108
Heavy Atom Count:18
Complexity:271

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=NN=C(O2)C3=CC(=CC=C3)F

Technology Process of 2-(3-Fluorophenyl)-5-phenyl-1,3,4-oxadiazole

There total 5 articles about 2-(3-Fluorophenyl)-5-phenyl-1,3,4-oxadiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 171796-92-2
C₁₄H₁₁FN₂O

: 62681-97-4
2-(3-fluorophenyl)-5-phenyl-1,3,4-oxadiazole

Guidance literature:: With oxygen; copper(II) bis(trifluoromethanesulfonate); caesium carbonate; In N,N-dimethyl-formamide; at 110 ℃; for 12h;
DOI:10.1021/ol202409r

Reference yield:

: 499-55-8
3-fluoro-benzoic acid hydrazide

: 93-97-0
benzoic acid anhydride

: 62681-97-4
2-(3-fluorophenyl)-5-phenyl-1,3,4-oxadiazole

: 455-38-9
3-fluorobenzoic acid

Guidance literature:: Multistep reaction;
DOI:10.1016/j.tet.2006.08.016

Reference yield:

: 613-94-5
benzoic acid hydrazide

: 456-48-4
3-Fluorobenzaldehyde

: 62681-97-4
2-(3-fluorophenyl)-5-phenyl-1,3,4-oxadiazole

Guidance literature:: Multi-step reaction with 2 steps

1: ethanol / Reflux

2: oxygen; copper(II) bis(trifluoromethanesulfonate); caesium carbonate / N,N-dimethyl-formamide / 12 h / 110 °C

With oxygen; copper(II) bis(trifluoromethanesulfonate); caesium carbonate; In ethanol; N,N-dimethyl-formamide;
DOI:10.1021/ol202409r