α-Butylpiperonyl Alcohol

Base Information

• Chemical Name: α-Butylpiperonyl Alcohol
• CAS No.: 5422-01-5
• Molecular Formula: C12H16 O3
• Molecular Weight: 208.257
• Mol file: 5422-01-5.mol

Synonyms:Piperonylalcohol, a-butyl- (6CI,8CI);1-(1,3-Benzodioxol-5-yl)-1-pentanol; NSC 6605; a-Butylpiperonyl alcohol

Chemical Property of α-Butylpiperonyl Alcohol

Chemical Property:

• Vapor Pressure: 0.000128mmHg at 25°C
• Boiling Point: 320.9°Cat760mmHg
• Flash Point: 147.9°C
• PSA: 38.69000
• Density: 1.149g/cm³
• LogP: 2.63890
• Solubility.: Chloroform,

Purity/Quality:

99%min ^*data from raw suppliers

α-ButylpiperonylAlcohol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Intermediate in the preparation of insecticides, fungicides, and other pesticides.

Technology Process of α-Butylpiperonyl Alcohol

There total 6 articles about α-Butylpiperonyl Alcohol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

→ 1-(benzo[d][1,3]dioxol-5-yl)pentan-1-ol (5422-01-5)

Guidance literature:

Reference yield: 94.2%

1-bromo-butane (109-65-9) + piperonal (120-57-0,30024-74-9) → 1-(benzo[d][1,3]dioxol-5-yl)pentan-1-ol (5422-01-5)

Guidance literature:

1-bromo-butane; With magnesium; In diethyl ether; at 0 - 5 ℃;

piperonal; In diethyl ether;

DOI:10.1016/j.tetasy.2005.07.009

Reference yield: 75.0%

1,3-benzodioxole-5-carboxylic acid 2-pyridinyl ester + n-butylzinc chloride (42930-39-2) → 1-(benzo[d][1,3]dioxol-5-yl)pentan-1-ol (5422-01-5)

Guidance literature:

With bis(acetylacetonate)nickel(II); In N,N-dimethyl-formamide; at 0 - 50 ℃; for 22h; Inert atmosphere; Schlenk technique; Sealed tube;

DOI:10.1021/acs.orglett.9b00774

upstream raw materials:

n-butyllithium

piperonal

1-bromo-butane

butyl magnesium bromide

Downstream raw materials:

MDPV

1-(benzo[d]-1,3-dioxol-5-yl)pentan-1-one

(+/-)-(1R*)-1-Bromo-1-(3,4-methylenedioxybenzoyl)butane

N-(1-(benzo[d][1,3]dioxol-5-yl)pentyl)-4-methylbenzenesulfonamide

Refernces

• 1、 Suzuki, Masaki,Deschamps, Jeffrey R.,Jacobson, Arthur E.,Rice, Kenner C.. "Chiral resolution and absolute configuration of the enantiomers of the psychoactive designer drug 3,4-methylenedioxypyrovalerone". . p. 287 - 293. Retrieved 2015/03/30.
• 2、 Koul, Surrinder,Koul, Jawahir Lal,Singh, Budh,Kapoor, Munish,Parshad, Rajinder,Manhas, Kuldeep S.,Taneja, Subhash C.,Qazi, Ghulam N.. "Trichosporon beigelli esterase (TBE): A versatile esterase for the resolution of economically important racemates". . p. 2575 - 2591. Retrieved 2007/10/03.