2-Chloro-6-(1H-pyrrol-1-yl)benzoic acid

Base Information

Chemical Name:2-Chloro-6-(1H-pyrrol-1-yl)benzoic acid
CAS No.:54779-76-9
Molecular Formula:C11H8ClNO2
Molecular Weight:221.6397
Hs Code.:2933990090
Mol file:54779-76-9.mol

Synonyms:T 9078;1-(2-carboxy-3-chlorophenyl)pyrrole;2-chloro-6-pyrrol-1-yl-benzoic acid;1-(3-Chlor-2-carboxyphenyl)-pyrrol;2-chloro-6-(1h-pyrrol-1-yl)benzoic acid;

Suppliers and Price of 2-Chloro-6-(1H-pyrrol-1-yl)benzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-Chloro-6-(1H-pyrrol-1-yl)benzoic acid

Chemical Property:

Vapor Pressure:1.19E-06mmHg at 25°C
Boiling Point:386°Cat760mmHg
Flash Point:187.3°C
PSA：42.23000
Density:1.32g/cm³
LogP:2.82890

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-Chloro-6-(1H-pyrrol-1-yl)benzoic acid

There total 4 articles about 2-Chloro-6-(1H-pyrrol-1-yl)benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 41910-45-6
1-(3-chloro-phenyl)-1H-pyrrole

: 124-38-9,18923-20-1
carbon dioxide

: 54779-76-9
1-(2-carboxy-3-chlorophenyl)pyrrole

Guidance literature:: 1-(3-chloro-phenyl)-1H-pyrrole; With n-butyllithium; N,N,N',N'',N'''-pentamethyldiethylenetriamine; In tetrahydrofuran; at -75 ℃; for 1h;

carbon dioxide; In tetrahydrofuran; diethyl ether; at 20 ℃; Further stages.;
DOI:10.1039/b100008j

Reference yield:

: 41910-45-6
1-(3-chloro-phenyl)-1H-pyrrole

: 124-38-9,18923-20-1
carbon dioxide

: 54779-76-9
1-(2-carboxy-3-chlorophenyl)pyrrole

: 232275-65-9
1-(4-Carboxy-3-chlorophenyl)pyrrole

Guidance literature:: 1-(3-chloro-phenyl)-1H-pyrrole; With 2,2,6,6-tetramethylpiperidinyl-lithium; In tetrahydrofuran; at -75 ℃; for 1h;

carbon dioxide; In tetrahydrofuran; diethyl ether; at 20 ℃; Further stages.;
DOI:10.1039/b100008j

Reference yield:

: 108-42-9
3-chloro-aniline

: 54779-76-9
1-(2-carboxy-3-chlorophenyl)pyrrole

Guidance literature:: Multi-step reaction with 2 steps

1.1: 58 percent / acetic acid

2.1: BuLi; N,N,N',N'',N''-pentamethyldiethylenetriamine / tetrahydrofuran / 1 h / -75 °C

2.2: 75 percent / tetrahydrofuran; diethyl ether / 20 °C

With n-butyllithium; N,N,N',N'',N'''-pentamethyldiethylenetriamine; In tetrahydrofuran; acetic acid;
DOI:10.1039/b100008j